Diarrhoea Flashcards
What is the epidemiology of gastro enteritis?
Contamination of food Storage of produce Campylobacter Travel related infections Person to person
What is the most common pathogen to cause food poisoning?
Campylobacter
What are the body’s defences against enteric infections?
Hygiene
Stomach acidity
Normal flora
Immunity
What are the different types of diarrhoea?
Non-inflammatory/secretory (Cholera)
Inflammatory (Shigella dysentery)
Mixed picture (C diff)
What is the clinical feature of non inflammatory diarrhoea?
Frequent watery stools with little abdominal pain
What is the treatment for non inflammatory diarrhoea?
Rehydration
How does cholera cause diarrhoea?
Increases cAMP levels and Cl secretion
How does inflammatory diarrhoea differ from non inflammatory?
Inflammatory toxin damage and mucosal destruction
Non inflammatory is secretory toxin mediated
How is inflammatory diarrhoea treated?
Mainly rehydration
Antimicrobials
What are the differential diagnoses for diarrhoea?
Inflammatory bowel disease
Carcinoma
Spurious diarrhoea secondary to constipation