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Infection > Antimicrobial Chemotherapy > Flashcards

Antimicrobial Chemotherapy Flashcards

1
Q

What patient characteristics have to be taken into account when prescribing medications?

A 
Age 
Renal function 
Liver function 
Immunocompromised 
Pregnancy 
Known allergies
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2
Q

What are the most common bacterial causes of pneumonia?

A 
Streptococcus pneumonia 
Haemophilus influenzae 
Staphylococcus aureus 
Klebsiella pneumonia 
Moraxella catarrhalis 
Mycoplasma pneumonia 
Legionella pneumonia 
Chlamydia pneumonia
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3
Q

What does bactericidal mean?

A

Act on cell wall
Kill organisms
Indications include neutropenia, meningitis and endocarditis

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4
Q

What does bacteriostatic mean?

A

Inhibit protein synthesis
Prevent corny growth
Require host immune system to “mop up” residual infection
Useful in toxin-mediated infection

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5
Q

What adverse allergic reaction effect can occur with medication?

A 
Anaphylactic shock 
Rash 
Drug fever 
Serum sickness 
Erythema nodosum 
Steven-Johnson syndrome
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6
Q

What are the common gastrointestinal adverse effects from medication?

A

Nausea
Vomiting
Diarrhoea

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7
Q

What are the neurological adverse effects from medication?

A 
Ototoxicity 
Optic neuropathy 
Convulsions 
Encephalopathy 
Peripheral neuropathy
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8
Q

What are the haematological adverse effects from medication?

A

Marrow toxicity

Megaloblastic anaemia

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9
Q

What are the antimicrobial classes of drugs?

A 
Penicillins (Beta lactams) 
Cephalosporins (Beta lactams) 
Aminoglycosides 
Macrolides 
Quinolones 
Glycopeptides 
Anti fungals 
Anti virals 
Immunoglobulin
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10
Q

What are the 3 mechanisms which antimicrobial drugs use to work?

A

Inhibition of cell wall synthesis
Inhibition of protein synthesis
Inhibition of nucleic acid synthesis

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11
Q

What are the common penicillins used as medication?

A 
Benzylpenicillin 
Penicillin V 
Amoxicillin 
Flucloxacillin 
Co amoxiclav 
Piperacillin 
Tazobactam
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12
Q

What are the main cephalosporins used as medication?

A 
Cefradine 
Cefuroxime 
Ceftriaxone 
Cefotaxime 
Ceftazidime
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13
Q

What are the main ahminoglycosides used as medication?

A

Gentamicin

Amikacin

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14
Q

What are the main macrolides used as medication?

A

Clarithromycin
Erythromycin
Azithromycin

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15
Q

What are the main quinolones used as medication?

A

Ciproflaxacin
Levoflaxacin
Moxiflaxacin

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16
Q

What are the main glycopeptides used as medication?

A

Vancomycin

Teicoplanin

17
Q

What are the other main antibiotics used as medication?

A 
Clindamycin 
Tetracycline 
Doxycycline 
Rifampicin 
Metronidazole 
Linezolid
18
Q

What are the main groups of anti fungal therapy used as medication?

A

Azoles
Polyenes
Echinocandins
Terbinafine

19
Q

What are the azole anti fungal therapy used as medication?

A

Fluconazole
Itraconazole
Voriconazole

20
Q

What are the polyenes used as anti fungal therapy?

A

Amphotericin

Nystatin

Infection (12 decks)

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