diabetic medications Flashcards
Metform MOA and risk?
biguanide-stop gluconeogenesis in liver and decrease intestinal uptake of glucose
how much does one ampule of d50 raise glucose?
how much sugar is in it
25 grams of suture. raises it 100-150 mg/dl
MOA sulfonylureas?? example of one/
glipizide
stimulate beta cells to make insulin(risk hypoglycemia)
MOA of thiazolidinediones? exmaple of one?
promotes insulin sensitivity and increase HDL
rosiglitazone
can cause weight gain
Meglitinides MOA. example of one ?
increase beta cell secretion of insulin
repaglinide
GLP1 agonist
decrease glucogan secretion and increase insulin secretion.
decrease gastric emptying. diet suppression
Ozempic or semiglutide
DPP4 inhibitor example and moa
junivia
inactivation of GLP1