Diabetes Summary Slide Facts

Question 1

Metformin

Answer 1

First line therapy; Decreases hepatic glucose production, decreased
intestinal glucose absorption, and increases insulin sensitivity and peripheral glucose
uptake and utilization

Question 2

Sulfonylureas

Answer 2

stimulate insulin secretion by pancreatic beta cells

Question 3

TZDs

Answer 3

decreases hepatic glucose output by decreasing insulin resistance in the periphery

Question 4

DPP-4 inhibitors

Answer 4

increases incretin hormone presence; similar mechanism of action as
GLP-1 agonists

Question 5

GLP-1 agonists -

Answer 5

• increase insulin release in the presence of elevated glucose and
  decreased appetite

Question 6

SGLT2 inhibitors

Answer 6

Decrease reabsorption of sugar in the kidneys

Question 7

Insulin

Answer 7

Works like normal insulin in the body; dosage and regimen varies by product