Antiviral

Question 1

Viruses are

Answer 1

intracellular: they invade healthy cells

Question 2

Antiviral drugs may affect

Answer 2

healthy cells in addition to viruses

Question 3

Antiviral drugs work by (three items)

Answer 3

 Interfering with viral nucleic acid synthesis and/or regulation
 Interfering with ability of virus to bind to cells
 Stimulating the body’s immune system

Question 4

Two types of anivruals

Answer 4

nonretrovirals used to treat viruses other than HIV and Antiretrovirals used to treat HIV

Question 5

Antiviral drugs act to reduce

Answer 5

viral load and symptoms but no direct cure

Work best in immunocompetent individuals

Question 6

synthetic nucleoside analogue prototype drug used to treat herpes infections including
HSV 1 and 2 and varicella similar agents and have the advantage of fewer daily doses

Answer 6

Acylovir

Question 7

Acylovir is superior in treating ____ but not effective in treating ___

Answer 7

shingles, chicken pox

Question 8

Acylovir and related durgs are dosed

Answer 8

differently for initial infections, recurrent infections and episodice infections.

Question 9

The two neuraminidase inhibitors used most often in this country to treat influenza include

Answer 9

oseltamivir

and zanamivir

Question 10

The initial drug regimen that is recommended to treat HIV includes

Answer 10

Three active drugs from at least 2

different classes:

Question 11

HIV regiment includes

Answer 11

2 nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) paired with 1 of the following:
 a non-nucleoside reverse transcriptase inhibitor (NNRTI)
 a boosted protease inhibitor (PI), or
 a boosted or unboosted integrase strand transfer inhibitor (INSTI)