Antidepressant Pharmacotherapy Flashcards
median age for depression
30 years
leading cause of disability ages 15-44 and worldwide
mental illness
10 million or 4.2% of adults
10 million or 4.2% of adults
Suicide stats
10th leading cause of death in the U.S.
the 3rd leading cause of death for people aged 10–24
2nd leading cause of death for people aged 15–24
for about 50% of indviduals mental illness manifests by
14 years
women have
twice the rate of depression than men do
what ethic group has lowest incidence of depression
asain men
Conditions associated with MH Illness
Hypothyroidism Dementia, stroke Rheumatoid arthritis CHF, MI Vitamin B-12 deficiency Cancer Parkinson’s Disease DM
Drugs associated with MH illness
Alcohol/Substance use Antihypertensives Antiparkinsonian agents Hormonal preparations Anticancer agents Psychotropic agents
Risk Factors for Depression first four
Prior episode of depression
FMH of mood disorders
Prior suicide attempt
Current substance abuse
risk factors for depression last three
Medical neurological comorbidity
Lack of social support
Stressful life events
DSM-5 depression dx critera
One or both for 2 weeks: Depressed, irritable mood Loss of interest or pleasure AND 3-4 of the following symptoms: Change in weight/appetite Change in sleep pattern Agitated/restless Fatigue/loss of energy Feelings of worthlessness or guilt Difficulty with concentration of memory Frequent thoughts of death or suicide Classification of Depression
History and assessment first four
Identify presenting symptoms Establish the course of the illness Obtain: PMH and medication history, FMH, psychosocial history Assess physical status
History and assessment last three
Establish psychological baseline
Assess for suicidality/thoughts of harm
Obtain laboratory baseline
Mood disorders =
neurotransmitter deficiency
