diabetes Flashcards
uses of blood glucose
muscle storgae enegy source storage of fat liver storgane energy for CNS/brian excretion in utine
diabetes mellitus
metabolic disorder of carbohydrate metabolism
characteristics of diabetes mellits
hyperglycaemia (increased blood glucose)
high mrbidity and mortality
blood glucose levels normal vs diabetes and after meal
Normal fasting conditions - 3-5mmol/l - less than 10mmol/l 90 mins post food Diabetic fasting conditions - 4-7mmol/l - greater than 20mmol/l - hyperglycaemia
signs of diabetes
- blurry vision
- increase thirst and need to urinate
- feeling tired or ill
- recurring skin, gum, bladder infections
- dry, itchy skin
- unexpected weight loss
- slow healing cuts and bruises
- loss of feeling in hands/feet
types of diabetes
1) Type I
- insulin dependant
2) Type II
3) Gestational diabetes
4) impaired glucose tolerance (IGT) and impaired fasting glycaemia (IFG)
- prediabetic conditions
type 1 diebtees
heritable genetic component
- lack of insulin production
affects islets of langerhams
beta cells killed by antibodies therefore lack of insulin
type 2
non insulin dependant or adult onset
affects production of insulin or response to insulin
- genetic and environmentals succeptibilty
obesity implicated
main stymptoms of type 2 and what do they man
1) Polyuria
- frequent urination due to osmotic diuresis
2) Polydipsia
- increased thirst and increased fluid intake due to polyuria
3) Polyphagia
- increased appetite
Other symptoms
- dry mouth
- itchiness
- increased incidence of thrush eg candida
- cramps
- skin infections
gestational diabetes
occurs in pregancies
predisposing factors to gestational diabetes and symptoms
- age (generally 35 over has a risk)
- ethnic group
- obesity
no clear sytoms
sometimes classic diabetes once
cause of gestational diabetes
- hormonal changed can make cells less responsive to insulin
- increased resistance to insulin
Increased blood glucose
Long term effect - larger babies
- mum at risk of type 2 diabetes
prediabetes
precursor to diabetes
associated with obestity0
- abnormally high blood glucose but not enough symptoms to diagnose
forms of prediabetes
1) impaired fasting glycaemia
2) impaired glucose tolerance
impaired fasting glycaemia
elevated fasting blood glucose but not high enough to classify as diebetes