developmental Flashcards
urinary and internal repro organs from
intermediate mesoderm
Y chrom
contains SRY gene codes for TDF
testes indifferent stage
- genital ridge form from intermediate mesoderm and overylying epi
- epi (Cx) grows into underlying mesoderm to form primitive sex cords (medulla)
- PGCs migrate to genital ridge wk 4-6, if they do not migrate gonads will not form
medulla formation male
testes
primitive sex cords reamin solid until puberty when canalize forming the seminiferous tubles, tubuli recti, and rete testes
testes secrete T by wk 8
Cx formation male
forms tunica albuginea
descent of testes
controlled by T
gubernaculum thick lig that attaches to caudal pole of testes to ant body wall (future site of deep inguinal ring)
process vaginalis- evagination of peritoneum that passes thry abdominal wall lateral to site of attachement of gubernaculum
process vaginalis and gubernaculum pulled thru abdominal wall forming inguinal canal
proximal portion of process vaginalis closes, distal portion forms tunica vaginalis around testes
genital ducts indifferent stage
2 duct systems from intermediate mesoderm
mesonephric (wolffian) -> induced to form male ducts and glands by T
paramesonephric (mullarian) -> inhibited by AMH produced from sertoli cells
mesonephric tubules
become efferent ductules and appendix of epididymis
mesonephric ducts
epididymis, ductus deferens, ejaculatory duct, seminal vesicle
urethra
gives rise to prostate and bulbourethral glands
paramesonephric duct
regresses except for appendix of testes and prostatic utricle
external genitalia
fully differentiated at 12th wk, under influence of T and DHT
anal folds
anus
genital tubercle
elongates to form glans penis
urethral folds
shaft, root of penis and penile urethra
elongates w/genital tubercle
urethral groove is an open groove on ventral penis
later 2 folds fuse to form penile urethra
remaining portion of urethra is formed by ectodermal cells growing inward
labioscrotal swellings
scrotum
scrotal septum forms where the 2 swellings fuse