Development of the Central Nervous System Flashcards

1
Q

How does the neural plate form?

A

Notochord stimulates differentiation of overlying ectoderm > neuroectoderm
Neuroectoderm forms thickened structure = neural plate

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2
Q

How does the neural tube form?

A

Neural plate > neural folds > fuse in midline to form neural tube

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3
Q

How does the neural crest form?

A

Some cells from fusing neural folds migrate and form neural crest

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4
Q

What is neurulation?

A

Formation of neural tube

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5
Q

By when is neurulation complete?

A

End of week 4

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6
Q

When do the primary primitive vesicles appear at the cranial end of the neural tube?

A

Week 5

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7
Q

What are the three primary primitive vesicles that eventually form the brain and cerebellum?

A

Prosencephalon
Mesencephalon
Rhombecephalon

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8
Q

What are the secondary vesicles derived from the prosencephalon?

A

Telencephalon

Diencephalon

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9
Q

What are the neural derivatives of the telencephalon?

A

Cerebral hemispheres

Globus pallidus

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10
Q

What are the cavity derivatives of the telencephalon?

A

Lateral ventricle

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11
Q

What are the neural derivatives of the diencephalon?

A

Thalamus
Hypothalamus
Epithalamus

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12
Q

What are the cavity derivatives of the diencephalon?

A

3rd ventricle

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13
Q

What are the secondary vesicles derived from the mesencephalon?

A

Mesencephalon

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14
Q

What are the neural derivatives of the mesencephalon?

A

Midbrain

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15
Q

What are the cavity derivatives of the mesencephalon?

A

Cerebral aqueduct

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16
Q

What are the secondary vesicles derived from the rhombencephalon?

A

Metencephalon

Myelencephalon

17
Q

What are the neural derivatives of the metencephalon?

A

Pons

Cerebellum

18
Q

What are the cavity derivatives of the metencephalon?

A

Upper part of 4th ventricle

19
Q

What are the neural derivatives of the myelencephalon?

A

Medulla

20
Q

What are the cavity derivatives of the myelencephalon?

A

Lower part of 4th ventricle

Central canal

21
Q

Into what do neuroderm cells differentiate?

A

Neurons

Glia

22
Q

What forms the spinal cord?

A

Caudal end of neural tube

23
Q

What forms the dorsal horns of the spinal cord?

A

Cells on dorsal side of caudal neural tube > alar plate > dorsal horns

24
Q

What forms the ventral horns of the spinal cord?

A

Cells on ventral side of caudal neural tube > basal plate > ventral horns