Development of the Central Nervous System Flashcards
How does the neural plate form?
Notochord stimulates differentiation of overlying ectoderm > neuroectoderm
Neuroectoderm forms thickened structure = neural plate
How does the neural tube form?
Neural plate > neural folds > fuse in midline to form neural tube
How does the neural crest form?
Some cells from fusing neural folds migrate and form neural crest
What is neurulation?
Formation of neural tube
By when is neurulation complete?
End of week 4
When do the primary primitive vesicles appear at the cranial end of the neural tube?
Week 5
What are the three primary primitive vesicles that eventually form the brain and cerebellum?
Prosencephalon
Mesencephalon
Rhombecephalon
What are the secondary vesicles derived from the prosencephalon?
Telencephalon
Diencephalon
What are the neural derivatives of the telencephalon?
Cerebral hemispheres
Globus pallidus
What are the cavity derivatives of the telencephalon?
Lateral ventricle
What are the neural derivatives of the diencephalon?
Thalamus
Hypothalamus
Epithalamus
What are the cavity derivatives of the diencephalon?
3rd ventricle
What are the secondary vesicles derived from the mesencephalon?
Mesencephalon
What are the neural derivatives of the mesencephalon?
Midbrain
What are the cavity derivatives of the mesencephalon?
Cerebral aqueduct
What are the secondary vesicles derived from the rhombencephalon?
Metencephalon
Myelencephalon
What are the neural derivatives of the metencephalon?
Pons
Cerebellum
What are the cavity derivatives of the metencephalon?
Upper part of 4th ventricle
What are the neural derivatives of the myelencephalon?
Medulla
What are the cavity derivatives of the myelencephalon?
Lower part of 4th ventricle
Central canal
Into what do neuroderm cells differentiate?
Neurons
Glia
What forms the spinal cord?
Caudal end of neural tube
What forms the dorsal horns of the spinal cord?
Cells on dorsal side of caudal neural tube > alar plate > dorsal horns
What forms the ventral horns of the spinal cord?
Cells on ventral side of caudal neural tube > basal plate > ventral horns
