Development of Head, Neck and Oral Cavity Flashcards
in embryonic folding the _______
folding is when the head and tail regions bend towards each other in a ventral direction
craniocaudal/longitudinal
a _______ folding is when the left and right sides of the embryo fold ventrally towards the midline, fuse and form a cylindrical embryo
lateral/transverse
neurulation is the formation of the ________ by converting the _______ into the _______
central nervous system, neural plate, neural tube
during neurulation the lateral edges of the neural plate fold _______ forming the midline neural _______
dorsally, groove
the neural groove is converted into the neural tube by the folding edges meeting and _______ at the dorsal midline
fusing
the notochord forms from mesoderm cells soon after gastrulation and signals cells of the ________ at the neural plate to start infolding, this causes the neural plate to fuse and _______ to form the neural tube
ectoderm, disconnect
somites are epithelial balls of cells formed in segmental pairs along the neural tube from the ________ which eventually differentiate into the _______, muscles of the ______ and _______, and _______ of the skin
paraxial mesoderm, vertebrate, back, body wall, dermis
fusion of the neural plate begins at day 22 at the ______ region or the ______ somite
cervical, 5th
fusion of the neural plate proceeds ______ and _______ at the same time
cranially, caudally
at day 23 of neurulation the cranial and caudal neuropores are still open to the ________
amniotic cavity
the closure of the cranial neuropore happens _______ the closure of the caudal neuropore
before (days 25 and 28 respectively)
spina bifida is a neural tube defect that results from the ______ neuropore failing to close
caudal
anencephaly is a neural tube defect that results from the ______ neuropore failing to close which allows neural tissue to be exposed to amniotic fluid causing _______
cranial, necrosis
addition of _______ into a gestational parents prenatal diet as a preventative measure to anencephaly
folic acid
the endoderm will form the ________, _______, ________ gland, ________ cavity, _______ tube, ________, and ________ gland
trachea, pharynx, thyroid, tympanic, phyaryngotympanic, tonsils, parathyroid
the paraxial mesoderm will form the _______ of the head, and ________, and the lateral mesoderm will form the _________ and _______ of the viscera
muscle, connective tissue, connective tissue, muscle
the ectoderm will form the ________, ______ of the teeth, internal _______, lens of the _______, cranial and sensory _____ and ______, ________ arch cartilage, head ________, _________ and __________
pituitary, enamel, ear, eye, ganglia, nerves, pharyngeal, mesenchyme, connective tissue, retina
a placode is a thickening of _______ that will form into one of our _______ organs
ectoderm, sensory
stomodeum is the future _______
mouth
the ___________ or anterior part of the skull is derived from mesenchyme that came from _______ or more specifically _______
viscerocranium, ectoderm, neural crest cells
the _________ or posterior part of the skull is derived from mesenchyme that came from the ________ or more specifically _________
neurocranium, mesoderm, paraxial mesoderm
the ectoderm neural crest cells of the viscerocranium the contains the _______ for our sensory organs and ganglia
placodes
each placode will have its own bar of _______, its own ________ and its own ________
cartilage, cranial nerve, blood supply
the 5th aortic arch is _______ meaning never forms or is just extremely tiny
transient
the ________ provide the pathway for the neural crest cells to migrate which is important in palate, face and heart development
aortic arches
DiGeorge syndrome or ____________ syndrome or _______ is a disease caused by the failure of neural crest cells to migrate due to a _______ chromosomal deletion
velocardiofacial, catch-22, 22nd
DiGeorge syndrome can cause ______, _______ or ______ deformities
facial, palatal, heart
transposition of the great arteries is caused by DiGeorge syndrome and causes _______ to not be distributed throughout the body due to the pulmonary trunk being connected to the left ventricle and the aorta being connected to the right (which is supposed to be switched)
oxygen
pharyngeal arches are bars of mesenchyme derived from the _______ and ______ that form 4/5? pairs around the ________ covered by ________ externally and _______ internally
mesoderm, neural crest cells, pharynx, ectoderm, endoderm
the pharyngeal arches, clefts and pouches will eventually form the ________
mandible