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Anatomical Sciences Exam 2 > dentin and pulp complex > Flashcards

dentin and pulp complex Flashcards

1
Q

dentin has some ______ (mechanically supports harder overlying enamel) and has tight scalloped ______

A

elasticity, dentinoenamel junction

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2
Q

dentin by weight is _____ inorganic material, ______ organic material and ____ water

A

70%, 20%, 10%

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3
Q

the inorganic material of dentin includes ________ and the organic material includes ______ collagen and _______ matrix proteins

A

calcium hydroxyapatite crystals, type 1 (3 and 4), non-collagenous

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4
Q

in dentin type ______ collagen forms scaffold for mineral, although type ______ is amongst the first secreted

A

I, III

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5
Q

primary dentin includes _____ dentin and ______ dentin

A

circumpulpal, mantle

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6
Q

circumpulpal dentin includes _______ dentin and _______ dentin

A

peritubular, intertubular

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7
Q

mantle dentin forms the ______

A

dentinoenamel junction

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8
Q

secondary dentin is deposited after _____ formation

A

root

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9
Q

tertiary dentin is ______ dentin containing odontoblasts that is formed in reaction to a stimulus like caries or dental procedure

A

reparative

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10
Q

dentin forms much of the tooth and is similar to ____

A

bone

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11
Q

dentin contains _______ located on the _____ surface of dentin adjacent to the pulp

A

odontoblasts, inner

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12
Q

peritubular dentin is found at the _____ of the tubules and is _____ mineralized

A

walls, highly

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13
Q

intertubular dentin is found between the ______ and is _____ mineralized

A

tubules, highly

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14
Q

the primary dentin (mantle + circumpulpal) is formed before completion of the _______ and is rapidly _____ and _______ mineralized

A

apical foramen, formed, highly

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15
Q

the circumpulpal dentin is the main body of the ______ dentin containing tubules and is formed after the ______ dentin

A

primary, mantle

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16
Q

mantle dentin is the outermost layer near ________ underneath the enamel and is the ______ dentin formed

A

dentinoenamel junction, first

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17
Q

secondary dentin is formed after the completion of the _______ and is _____ formed and _____ mineralized

A

apical foramen, slower, less

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18
Q

tertiary dentin is formed as a result of localized ______ to exposed dentin and has irregular course of tubules that are not well _______ and placed ______

A

injury, organized, rapidly

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19
Q

canaliculus is a part of the primary dentin with cytoplasmic connection between ______ processes

A

odontoblast

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20
Q

predentin is ________, analogous to osteoid during bone formation and contains mostly collagen type ____ (lower levels of type ___ and ____), dentin _______, substratum for mineralization and the ______ secrete the collagen

A

unmineralized, I, III, V, phosphoprotein, odontoblasts

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21
Q

predentin is secreted at a rate of _____ per day

A

4um

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22
Q

Major noncollagenous matrix
proteins of dentin
– Dentin phosphoprotein/phosphophoryn (______)
– Dentin sialoprotein (____)
– Dentin glycoprotein (_____)
– Dentin matrix protein I (_____)
– ______
– Bone sialoprotein (______)
– _______

A

DPP, DSP, DGP, DMP1, Osteonectin, BSP, Osteopontin

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23
Q

secondary dentin develops after root _______, is a narrow band bordering the ______, deposits at around ______ per day, has fewer ______, and is formed at greater amounts near the roof of the _______ to protect the pulp horns

A

completion, pulp, 1um, tubules, pulp chamber

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24
Q

in tertiary dentin odontoblasts differentiate at site of injury and produce dentin with
______ and ______ tubules

A

sparse, irregular

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25
Q

Dentinogenesis begins during the bell
stage and dentin is a cellular product produced by ______

A

odontoblasts

26
Q

Odontoblasts differentiate from
ectomesenchymal cells of the _______ and need to differentiate into
protein secreting cells

A

dental papilla

27
Q

________ of the inner enamel epithelium induce odontoblast formation and differentiation.

A

Presecretory ameloblasts

28
Q

The process of dentinogenesis starts first in the ______ of the developing tooth (coronal dentin), then later in the ______ (root dentin), a process driven by Hertwig’s root sheath

A

cuspal region, root

29
Q

during the formation of odontoblasts, cells of the inner enamel epithelium reverse _____, ectomesenchymal cells adjoining the acellular zone rapidly ______ and ______ and become preodontoblasts and then odontoblasts, the odontoblasts differentiate and increase in size to occupy the acellular zone between the ______ and the presecretory ________.

A

polarity, enlarge, elongate, dental papilla, ameloblasts

30
Q

When presectory ameloblasts change
_______ then odontoblasts appear

A

polarity

31
Q

pre-odontoblasts proliferation and differentiation begins with the division of ______ cells, after mitosis one daughter cell remains undifferentiated while the other differentiates into an _______

A

precursor, odontoblast

32
Q

Deciduous teeth root dentin finishes _____
months after eruption and permanent teeth finishes _____ years after eruption

A

18, 2 – 3

33
Q

in preodontoblasts there is more cytoplasmic
organelles, including _______ endoplasmic reticulum and ________ and the nucleus becomes ______ within the cell, i.e., it is now
located at the _______ of the cell away from the inner enamel epithelium

A

rough, Golgi complexes, polarized, base

34
Q

secretory odontoblasts are tall columnar cells with extensive ______ endoplasmic reticulum, elaborate _______ and secretory vesicles, they synthesize and elaborate _______ and these cells now secrete Type ____ collagen
and ground substance extracellularly in
much the same way as fibroblasts.

A

rough, Golgi complexes , extracellular
material, I

35
Q

Unmineralized dentin is ______

A

predentin

36
Q

Odontoblasts elaborate a small
cellular process within the secreted
predentin which will become embedded in enamel at the dentinoenamel junction later and will be known as the ________

A

enamel spindle.

37
Q

As the odontoblasts migrate towards
the _____ as more dentin is formed
the odontoblastic processes becomes
longer and are embedded within the
dentine in ______

A

pulp, tubules

38
Q

First sign of dentinogenesis is deposition of _______ fibers initiating predentin formation which contain collagen type ____ fibers, with fibronectin

A

von (Von) Korff’s, III

39
Q

during dentinogenesis ________ is deposited, dentine matrix ______ then appear and vesicles grow and then release _____

A

collagen, vesicles, matrix

40
Q

Mineralization of dentin tends to occur in small, round discrete areas called
_______

A

calcospherites

41
Q

calcospherites eventually coalesce to form a globular solid mass of mineralized dentin but if they do not fuse completely, we see regions of uncalcified dentin called ________

A

inter- globular dentin

42
Q

Linear calcification forms when mineralization progresses ______

A

slowly

43
Q

Globular calcification occurs when there are mineralization _____ that continue to grow _____

A

foci, larger

44
Q

Sclerotic dentin occurs when the dentinal tubules become ______ and this dentin increases with _____

A

occluded, age

45
Q

Tubules in _______ may fill with bacteria, they stain darkly in histologic sections and odontoblast processes in these tubules may disintegrate leaving behind an empty tubules referred to as a ______

A

carious lesions, dead tract

46
Q

Odontoblasts deposit dentin in daily increments and every 5 days there is a change in orientation of collagen fibers resulting in the incremental lines of _______

A

von Ebner

47
Q

Contour lines _______ are exaggerated incremental lines that reflect changes in _______ status or ______ in the
individual during the period of dentinogenesis and _____ also
correlates with formation of a contour line

A

of Owen, nutritional, disease, birth

48
Q

The pulp is derived from the mass of the _______

A

dental papilla

49
Q

Dental pulp is ________ and has a pulp chamber and a root canal that terminates as _______

A

connective tissue, apical foramen

50
Q

pulp is connective tissue with 4 zones that include _______ layer, cell (partially) ______ zone of Weil, cell _____ zone and the _____ core

A

odontoblastic, “free”, rich, pulp

51
Q

the odontoblastic layer lines outer ______ wall and consists of cell bodies of odontoblasts, which may form ______ dentin, causing cell bodies to realign themselves; cell bodies of afferent axons from dentinal tubules located between cell bodies of odontoblasts

A

pulpal, secondary

52
Q

the cell free zone contains fewer cells than odontoblastic layer and the ________ and _______ are located here

A

nerve plexus of Raschkow, capillary plexus

53
Q

the cell rich zone contains increased density of cells compared with cell-free zone and more extensive ______

A

vascular supply

54
Q

the pulpal core is located in center of _______ and is similar to cell-rich zone with many cells and extensive _______

A

pulp chamber, vascular supply

55
Q

Other cells types in pulp include:
* ________ that make pulp matrix
* Undifferentiated ________ cells (dental pulp stem cells (DPSCs)). These cells are a rich resource for the dentin-pulp complex because they can transform into fibroblasts or odontoblasts if either cell population is reduced after injury.
* _________
* _________ (Mostly T)
* _________ cells (antigen presenting cells)

A

Fibroblasts, ectomesenchymal, Macrophages, Lymphocytes, Dendritic

56
Q

the extracellular matrix of pulp includes collagen (__ and ___) with matrix components
such as ________, _______, and ______

A

I, III, glycosaminoglycans, glycoproteins, water

57
Q

The pulp contains __________ plexi which describes blood vessels and the nerve plexus of ______ for nerve fibers

A

fenestrated capillary, Raschkow

58
Q

sensory nerve fibers can track with _______ processes into the dentin tubules for signaling

A

odotoblasts

59
Q

dentin/pulp complex is sensitive with the application of cold ____ or _____, mechanical _____ or _______ to dentin all result in pain

A

air, water, contacts, dehydration

60
Q

aging will cause a decrease in volume of
_______ due to continued deposition of dentin, reduction of _________, reduced cell _______ with an increase of fibrous bundles, loss of ______ and ______ sensitivity, and ______

A

pulp chamber, vascular supply, density, axons, pulp, calcifications

61
Q

________(calcified masses) can reduce the overall number of cells within the pulp and act as an impediment to débridement (removal of dead/unhealthy tissue)

A

Pulp stones

62
Q

aging can cause dentin to gradually reduce in ______, cause complete closure or translucent ______ dentin, increase _______, and cause ______

A

diameter, sclerotic, brittleness, dead tracts

Anatomical Sciences Exam 2 (11 decks)

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