Dermatology

Question 1

What are the 3 main layers of the skin?

Answer 1

-epidermis
-dermis
-subcutaneous tissue

Question 2

What is the function of the skin?

Answer 2

Epidermis acts a protective barrier, protects from bacteria etc

Question 3

What is the stratum corneum?

Answer 3

Outer keratin layer of the epidermis

Question 4

Where is stratum corneum thicker?

Answer 4

Palms of hand
Soles of feet

Question 5

Why does psoriasis present with plaques?

Answer 5

Increased cell turnover
Hyper proliferation of epidermis

Question 6

How can acne vulgaris be classified?

Answer 6

mild: open and closed comedones with or without sparse inflammatory lesions

moderate acne: widespread non-inflammatory lesions and numerous papules and pustules

severe acne: extensive inflammatory lesions, which may include nodules, pitting, and scarring

Question 7

What’s the treatment for mild-moderate acne vulgaris?

Answer 7

-12wk topical combination therapy:

-a fixed combination of topical adapalene with topical benzoyl peroxide
-a fixed combination of topical tretinoin with topical clindamycin
-a fixed combination of topical benzoyl peroxide with topical clindamycin

topical benzoyl peroxide may be used as monotherapy if these options are contraindicated

Question 8

What’s the treatment for moderate to severe acne vulgaris?

Answer 8

12-week course of one of the following options:
-a fixed combination of topical adapalene with topical benzoyl peroxide
-a fixed combination of topical tretinoin with topical clindamycin
-a fixed combination of topical adapalene with topical benzoyl peroxide + either oral lymecycline or oral doxycycline
-a topical azelaic acid + either oral lymecycline or oral doxycycline

tetracyclines should be avoided in pregnant or breastfeeding women and in children younger than 12 years of age