Contraception Flashcards
What are some methods of contraception?
Natural family planning (“rhythm method”)
Barrier methods (i.e. condoms)
Combined contraceptive pills
Progestogen-only pills
Coils (i.e. copper coil or Mirena)
Progestogen injection
Progestogen implant
Surgery (i.e. sterilisation or vasectomy)
What is the UKMEC?
UK Medical Eligibility Criteria
to categorise the risks of starting different methods of contraception in different individuals
What are the levels of UKMEC?
UKMEC 1: No restriction in use (minimal risk)
UKMEC 2: Benefits generally outweigh the risks
UKMEC 3: Risks generally outweigh the benefits
UKMEC 4: Unacceptable risk (typically this means the method is contraindicated)
What contraception should be avoided if there’s a risk factor of breast cancer?
Hormonal contraceptives
Copper coil or barrier methods should be used instead
What contraception should be avoided if cervical or endometrial cancer is a risk factor?
Intrauterine system e.g. Mirena coil
What contraception should be avoided if patient has Wilson’s disease?
Copper coil
What are some specific risk factors that makes you avoid combined contraceptive pill?
-Uncontrolled hypertension (particularly ≥160 / ≥100)
-Migraine with aura
-History of VTE
-Aged over 35 smoking more than 15 cigarettes per day
-Major surgery with prolonged immobility
-Vascular disease or stroke
-Ischaemic heart disease, cardiomyopathy or atrial fibrillation
-Liver cirrhosis and liver tumours
-Systemic lupus erythematosus and antiphospholipid syndrome
How long is contraception still required after a woman’s last period due to menopause?
2yrs if under 50
1yr over 50
What contraception advice should be given to perimenopausal women starting HRT
HRT does not prevent pregnancy
Added contraception is required
What age should the progesterone injection be stopped and why?
Before 50yrs due to osteoporosis risk
What contraceptive can be used to treat perimenopausal symptoms?
Combined contraceptive pill
Up to 50yrs
When does fertility return after childbirth?
21days after
What is lactational amenorrhea?
Women who are fully breastfeeding become amenorrhoeic
Effective contraception for up to 6 months
What contraceptions are safe and what should be avoided in breastfeeding?
Progesterone only pill and implant are safe
Combined contraceptive pill should be avoided
What is the mechanism of action for the combined oral contraceptive pill?
-Preventing ovulation (this is the primary mechanism of action)
-Progesterone thickens the cervical mucus
-Progesterone inhibits proliferation of the endometrium, reducing the chance of successful implantation
What hormones does the COCP contain?
Oestrogen
Progesterone
How does the COCP prevent ovulation?
Oestrogen and progesterone have a negative feedback effect on the hypothalamus and anterior pituitary, suppressing the release of GnRH, LH and FSH.
Without the effects of LH and FSH, ovulation does not occur. Pregnancy cannot happen without ovulation.
What are the two types of COCP?
Monophasic pills contain the same amount of hormone in each pill
Multiphasic pills contain varying amounts of hormone to match the normal cyclical hormonal changes more closely
What are some examples on monophasic COCP?
Microgynon contains ethinylestradiol and levonorgestrel
Loestrin contains ethinylestradiol and norethisterone
Cilest contains ethinylestradiol and norgestimate
Yasmin contains ethinylestradiol and drospirenone
Marvelon contains ethinylestradiol and desogestrel
What are some side effects of COCP?
-Unscheduled bleeding is common in the first three months and should then settle with time
-Breast pain and tenderness
-Mood changes and depression
-Headaches
-Hypertension
-Venous thromboembolism (the risk is much lower for the pill than pregnancy)
-Small increased risk of breast and cervical cancer, returning to normal ten years after stopping
-Small increased risk of myocardial infarction and stroke
What are the benefits of COCP?
-Effective contraception
-Rapid return of fertility after stopping
-Improvement in premenstrual symptoms, menorrhagia (heavy periods) and dysmenorrhoea (painful periods)
-Reduced risk of endometrial, ovarian and colon cancer
-Reduced risk of benign ovarian cysts
What are the missed pill rules for COCP?
Missing one pill (less than 72 hours since the last pill was taken):
-Take the missed pill as soon as possible (even if this means taking two pills on the same day)
-No extra protection is required provided other pills before and after are taken correctly
Missing more than one pill (more than 72 hours since the last pill was taken):
-Take the most recent missed pill as soon as possible (even if this means taking two pills on the same day)
-Additional contraception (i.e. condoms) is needed until they have taken the pill regularly for 7 days straight
-If day 1 – 7 of the packet they need emergency contraception if they have had unprotected sex
-If day 8 – 14 of the pack (and day 1 – 7 was fully compliant) then no emergency contraception is required
-If day 15 – 21 of the pack (and day 1 – 14 was fully compliant) then no emergency contraception is needed. They should go back-to-back with their next pack of pills and skip the pill-free period.
What is the mechanism of action for the traditional progesterone only pill?
-Thickening the cervical mucus
-Altering the endometrium and making it less accepting of implantation
-Reducing ciliary action in the fallopian tubes
What’s the mechanism of action for the Desogestrel only pill?
-Inhibiting ovulation
-Thickening the cervical mucus
-Altering the endometrium
-Reducing ciliary action in the fallopian tubes
What are some side effects of the POP?
Changes to bleeding schedule:
-20% have no bleeding (amenorrhoea)
-40% have regular bleeding
-40% have irregular, prolonged or troublesome bleeding
Breast tenderness
Headaches
Acne
What is there an increased risk of when taking POP?
-Ovarian cysts
-Small risk of ectopic pregnancy with traditional POPs (not desogestrel) due to reduce ciliary action in the tubes
-Minimal increased risk of breast cancer, returning to normal ten years after stopping