Dermatology

Question 1

Topical agent for pruritus-associated with atopic dermatitis or lichen simplex chronicus

Answer 1

Doxepin

Question 2

Residual drug persists up to ____ days following application of permethrin.

Answer 2

10 days

Question 3

It is recommended that permethrin 1% cream rinse (Nix) be applied undiluted to affected areas of pediculosis for ________ and then rinsed off with warm water.

Answer 3

10 minutes

Question 4

This is available for the treatment of external genital and perianal warts in adults, actinic keratoses on the face and scalp, and biopsy-proven primary superficial basal cell carcinomas on the trunk, neck, and extremities.

Answer 4

Imiquimod

Question 5

The mechanism of this drug’s action is thought to be related to its ability to stimulate peripheral mononuclear cells to release interferon alpha and to stimulate macrophages to produce interleukins-1, -6, and -8, and tumor necrosis factor-α (TNF-α).

Answer 5

imiquimod

Question 6

Imiquimod should be applied to the wart tissue ________ times per week and left on the skin for ________ hours prior to washing off with mild soap and water.

Answer 6

three times a week
6–10 hours

Question 7

Treatment with imiquimod should be continued until eradication of the warts is accomplished, but not for more than a total of _____ weeks.

Answer 7

16

Question 8

Treatment of superficial basal cell carcinoma with imiquimod consists of ____-times-per-week application of 5% cream to the tumor, including a 1 cm margin of surrounding skin, for a ______ course of therapy

Answer 8

five times per week
6-week course

Question 9

Maximum duration of prescribing potent topical steroids

Answer 9

2 weeks

Question 10

This is an oral phosphodiesterase 4 (PDE4) inhibitor that is effective in treating moderate to severe plaque psoriasis.

Answer 10

Apremilast

Question 11

This is a synthetic vitamin D3 derivative (available as a 0.005% cream, scalp lotion, and foam) that is effective in the treatment of plaque-type psoriasis vulgaris of moderate severity

Answer 11

Calcipotriene (Dovonex, Sorilux)

Question 12

What are the superpotent TCS?

Answer 12

Clobetasol propionate 0.05%
Betamethasone dipropionate 0.05%

Question 13

Class VII TCS

Answer 13

Hydrocortisone and Methylprednisolone

Question 14

TCS Class of Desonide 0.05%

Answer 14

Class VI (mild)

Question 15

Minoxidil side effects should be monitored especially for those with _____ disease

Answer 15

cardiac

Question 16

This is available as a 1% shampoo or lotion for pediculosis capitis or pubis

Answer 16

Lindane

Question 17

For pediculosis capitis or pubis, 30 mL of Lindane shampoo is applied to dry hair on the scalp or genital area for _____ minutes and then rinsed off.

Answer 17

4 minutes

Question 18

_________, N-ethyl-o-crotonotoluidide, is a scabicide with some
antipruritic properties

Answer 18

Crotamiton

Question 19

This is a straight-chain saturated dicarboxylic acid that is effective in the treatment of acne vulgaris and acne rosacea, and it also inhibit conversion of testosterone to DHT

Answer 19

Azelaic acid

Question 20

This temporarily eliminates S aureus nasal carriage by patients or health care workers, but results are mixed with respect to its ability to prevent subsequent staphylococcal infection.

Answer 20

Mupirocin

Question 21

This is a semisynthetic pleromutilin derivative effective in the treatment of uncomplicated superficial skin infection caused by group A β-hemolytic streptococci and S aureus, excluding MRSA.

Answer 21

Retapamulin (Altabax)

BID x 5 days

Question 22

This is derived from the sap of the Euphorbia peplus plant and has recently been approved for the topical treatment of actinic keratoses. Local skin reactions are to be expected with crusting, swelling, vesiculation, and possible ulceration.

Answer 22

Ingenol mebutate

Question 23

This is an α2-adrenergic agonist indicated for the topical treatment of persistent facial erythema of rosacea in adults 18 years of age or older.

Answer 23

Brimonidine (Mirvaso)

Question 24

This is a metabolite of the aromatic retinoid etretinate, is effective in the treatment of psoriasis, especially pustular forms. It is more teratogenic than isotretinoin and must be discontinued for 3 years prior to conception.

Answer 24

Acitretin (Soriatane)

Question 25

Used for treatment of pediculosis capitis of patients age > 6 months

Answer 25

Benzyl alcohol