Dermatology

Question 1

Identify the Skin lesion :
Dilated superficial blood vessels

Answer 1

Telangiectasia

Question 2

Characteristic lesion in scabies?

Answer 2

Burrows

Question 3

Identify the Skin lesion:
Raise, round , flat topped Erythematous papule or plaque, characteristically evanescent , representing short-lived vasodilation?

Answer 3

Wheal

Question 4

Functions and characteristics of the Epidermis? (3)

Answer 4

1. Cells are continually shred from the stratum corneum
2. It assists the immune system in warding off pathogen
3. Nourishment is mainly provided by diffusion

Question 5

95% of cells in the epidermis

Answer 5

Keratinocytes

Question 6

Mutation in the gene encoding this protein in atopic dermatitis is responsible for this characteristic defect.

Answer 6

Filaggrin

Question 7

Loss of cohesion between keratinocytes?

Answer 7

Atopic dermatitis

Question 8

Characteristic defect in atopic dermatitis that contributes to its pathophysiology.

Answer 8

Impaired epidermal barrier

Question 9

Common histologic finding in eczema?

Answer 9

Spongiosis ( intracellular edema in the epidermis)

Question 10

Acantholytic blister formed in Suprabasal layer of Epidermis manifesting as FLACCID blisters

Answer 10

pemphigus vulgaris

Question 11

Subepidermal blister with eosinophilic-rich infiltrate manifesting as large TENSE blisters on flexor areas?

Answer 11

Bullos phemphigoid

Question 12

Type of vitiligo that is usually unilateral and follows a dermatomal distribution.

Answer 12

Segmental vitiligo

Question 13

Features of Segmental vitiligo (4)

Answer 13

1. Mostly unilateral
2. Differs in cause and frequency of associated illness
3. Early onset and more rapid progression
4. Treatment in the same as that of non-segmental vitiligo

Question 14

The occurrences where in traumatized areas are often develop lesions of psoriasis

Answer 14

Koebner phenomenon

Question 15

Drugs that most commonly cause SJS-TEN (4)

Answer 15

1. Sulfonamides
2. Allopurinol
3. Anti-epileptics ( lamotrigine , phenytoin, carbamazepine)
4. NSAIDS (-oxicam)

Question 16

Percentage percentage of skin involvement of Steven-Johnson Syndrome vs TEN

Answer 16

<10% - SJS
10-30 %- SJS TEN Overlap
>30%- TEN

Question 17

Sign seen in SJS and pemphigus wherein manual manipulation of the skin of patients elicits separation of the epidermis?

Answer 17

Nikolsky sign

Question 18

Type of tissue that grows abnormally on Pyronie’s disease?

Answer 18

Collagen