Derm manifestations of systemic disease Flashcards

1
Q

What are the cutaneous associations with diabetes?

A

Acanthosis nigricans

Acral dry gangrene (fingers > toes)

Acral erythema

Carotenoderma (orange yellow skin colour)

Diabetic bullae

Diabetic cheiroarthropathy

Diabetic dermopahty (brown macules and patches on the shins)

Disseminated granuloma annularae

Eruptive xanthomas

NLD

Neropathic ulcers

Perforating disorders

Sclerodema

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2
Q

What are the dermatoses ass with metabolic syndrome?

A

Psoriasis

PCOS ○ Acanthosis nigricans
○ Acne vulgaris
Hirsutism

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3
Q

Dermatological manifestations of hyperthyroidism?

A

Skin:
- fine velvety smooth skin
- warm and moist (increased sweating)
- hyperpigmentation
- pruritis

Pretibial myxedema
Thyroid acropachy
Urticaria
Vitiligo

Fine thin hair
Diffuse alopecia
AA

Onycholysis
Koilonychia
Clubbing from thyroid acropachy

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4
Q

Dermatological manifestations of hypothyroidism?

A

Dry, rough, coarse skin
Cold and pale
Boddy and edematous skin (myedema)
Yellow discolouration as a result of carotenoderma
Easy bruising

Acquired Ichthyosis
Eruptive and/ or tuberous xanthomas
Increased incidence of vitiligo

Dull coarse adn birttle hair
Alopecia of the lateral thirds of the eyebrow
AA

Nails thin, brittle, striated
Slow growth
Onycholysis

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5
Q

Skin findings in Crohns diesase of UC

A

Directly Related
- cutanoues crohns
- fistulae (perianal / abdominal)
- apthos ulcers
- angular chelitis
- perianal skin tags

Associations:
- Erythema nodosum
- Cutaneous small vessel vasculitis
- Pustular vascultiis (Bowel associated dermatosis arthritis syndorme)
- Pyoderma gangrenosum
- Neutophillic dermatoses (sweets, acneiform lesions, panniculitis)
- pyostoma vegetans
- EBA
- psoriasis
- HS

Due to nutritional disorders
- scrodermatitis enteropathica like lesions

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6
Q

Cutaneous manifestations of Hep B /C

A

Cutaneous small vessel vasulitis
Cryoglobulinaemic vasculitis (C>B)
Urticarial vasculitis
PAN
necrotising livedo reticularis

Urticaria
Prutiris

PCT (C>B)

Lichen Planus
Necrolytic acral erythema
Gionotti crosti (B >C)

EM
EN (B >C)

Sacroidosis (C >B)

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7
Q

Cutaneous signs of rheumatoid arthritis

A

Rheumatoid nodules
Reactive granulomatous dermatitis

Neutrophillic dermatoses
- sweets
- rheumatoid neutrophillic dermatoses
- neutrophillic lobular panniculitis

Bywater lesions
Rheumatoid vasculitis
Intralymphatic histiocytosis
EED

comp of Rx:
- urticaria
- ISR
- psudoporphyria (NSAIDs)
- rheumatoid noulosis (MTx)

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