Depression, Anxiety, and Dementia Flashcards
Define mood
Sustained emotion that impacts our perception of the world and how we function in it
What neurotransmitters are involved in the neurobiology hypothesis?
Norepinephrine, dopamine, and seratonin
Conditions associated with major depressive disorder?
Neuro disorders, cancers, autoimmune, CV conditions
Risk factors for depression
previous depression, family history, lack of social support, stressful life event current substance use, medical comorbidity
When do you need medication for depression?
Suicidal, loss of function, impacts daily life
DSM 5 requirements for depression
Need 5
- Depressed mood or or loss of interest and pleasure
- Weight loss or gain
- Insomnia or hypersomnia
- Psychomotor agitation or retardation
- Fatigue or loss of energy
- Worthlessness or guilt
- Diminished ability to think or concentrate
- Reucurrent thought of death
Differential diagnosis of major depressive disorder?
Major depression with psychotic feature, bipolar disorder, dysthymic disorder, cyclothymic disorder, seasonal affective disorder, adjustment disorder with depressed mood, post part depression
What does SIG E CAPS
Sleep changes, interest lost, guilt, energy, cognition, appetite, psychomotor, suicide
Best treatment for depression?
Medication and psychotherapy
SSRIs medications
fluoxetine ( prozac)
Citlaopram (celexa)
Escitalopram (lexapro)
Paroxetine (paxil)
SSRI side effects?
motor restlessness, anxity and agitiation, insomnia, sedation sexual dysfunction, serotnin syndrome
What should you do for SSRi side effects?
Take them at night
TCA side effects?
Anticholinergic and sedative side effects
Major problem of TCA?
Cardiovascular toxicity with over dose
Atypical Antidepressants?
SNRI
Venlafaxine (effexor), duloxetine (cymbalta), nefazodone (serzone)
When do you stop antidepressants?
6-9 months after depression symptoms