Degeneration and Regeneration of the Nervous System Flashcards

1
Q

(PNS) axotomy that causes degeneration of distal axon and terminal is what type

A

wallerian degeneration

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2
Q

(PNS) retrograde effects on the cell body after axotomy are

A

chromatolysis

  • eccentric nucleus
  • dissolution of Nissl bodies (RER)
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3
Q

(PNS) what occurs in wallerian degeneration

A

distal process has no sustaining cell body, always dies

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4
Q

(PNS) regeneration process is

A

schwann cells form channels for regrowth of axons

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5
Q

(PNS) misaligned glial cells in regeneration can lead to:

A

neuroma formation

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6
Q

(CNS) transneuronal effects?

A

may be seen in major pathways (unlike in PNS where they are rare)

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7
Q

regeneration differences for CNS

A

true regeneration is rare because glial cells proliferate to fill space and block regrowth (scar tissue)

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