Cytokines Flashcards
where does IL-1 come from?
macrophages
where does IL-2 come from?
TH1 cells
where does IL-4 come from?
TH2 cells
which ILs come from TH2 as a main source?
IL-4
IL-6
IL-10
which ILs come from macrophages as a main source?
IL-1
IL-6
IL-8
IL-12
where does IL-12 come from?
dendritic cells
macrophages
B cells
where does IL-3 come from?
activated T helper cells
which interleukins with TNFalpha induce fever?
IL-1
IL-6
which IL stimulates T cells to differentiate into CTLS?
IL-2
what does IL-1 do?
induces fever
produces acute inflammation
what does IL-4 do?
class switching in B cells to IgE & IgG
what does IL-5 do?
activate eonisophils
what does IL-6 do?
induces fever
Th17 cell maturation
stimulates B cell differentiation
what is the function of IL-8?
chemotaxis for neutrophils
what is the function of IL-10?
inhibits Th1 cytokine production
an ‘anti-inflammatory’ cytokine
