CSF And Aqueous Humour Flashcards
This structure produces CSF
Choroid plexus epithelium
Csf is formed in the ____ and circulates in the ____ then absorbed into the ____
Ventricle
Subarachnoid space
Venous system
Function of csf
Brain cushion
Homeostasis - pH affects pulmonary ventilation and cerebral blood flow
Blood brain exchange of nutrients
Embryology ____ gives rise to the brain ventricles and spinal cord central canal
Cavity of the neural canal
Csf has lower concns of ____ and higher concns of _____ than blood
Glucose K+ Ca+ protein cholesterol cells - lower
Na and Cl - more
Flow of csf through the ventricular system =
Lateral ventricles Interventricular foramen (of monroe) 3rd ventricle Cerebral aqueduct (of Sylvius) 4th ventricle Median and 2x lateral apertures Subarachnoid space
Csf from subarachnoid space to venous system via
Arachnoid granulations
>
Superior sagittal sinus
Brain interstitial fluid drains to CSF through
Perivascular spaces
Brain parts without a BBB
Pineal gland
Circumventricular organs
Tumours of the ventricles -
Colloid cyst( often at interventricular foramen)
Ependymomas
Choroid plexus tumours
IIH aka
Features -
Idiopathic intracranial hypertension
Headache visual disturbance and papilloedema BUT wo the imaging features of hydrocephalus even though CSF P is up
What causes papilloedema?
Raised ICP is transmitted to subarachnoid space around optic nerve so it swells and bulges
Symptoms of papilloedema
Enlarged blind spot
Blurry vision
Obscurations
Vision loss
HCO3- function in aqueous humour
Buffers H+ produced by anaerobic glycolysis in lens and cornea
Path of aqueous humour from production to drainage
Epithelium of ciliary body in post chamber
Ant chamber
Trabecular meshwork and canal of Schlemm in iridocorneal angle
Scleral venous system
(Small bit is absorbed across retinal pigment epithelium)
