CS. Liver & Biliary Disease Flashcards
What vitamin is needed for the production of clotting factors?
Fat-soluble vitamin K
Signs of decompensated liver disease
Drowsiness
Ascites
Oedema
Signs of chronic liver disease
Gynaecomastia
Splenomegaly
Xanthomas and clubbing
What is jaundice?
Yellowing associated with accumulation of bilirubin in the skin
Outline the diagnostic thresholds for jaundice
Normal plasma bilirubin: 5-15mmol/L
Jaundice-level plasma bilirubin: >30mmol/L
What causes jaundice?
Liver and biliary disease
Haematological diseases
What classifications of jaundice is there?
Pre-hepatic (Haemolytic)
Hepatic (Hepatocellular)
Post-hepatic (Cholestatic)
Symptoms of alcoholic hepatitis
Unwell, jaundiced and anorexic
Treatment of alcoholic hepatitis
Abstinence is only treatment
What is alcoholic cirrhosis?
Scarring of the liver
Permanent damage
How are HepB and HepC transmitted?
Parenterally; HCV less easier than B
When is risk of chronic infection of HepB increased?
If contracted in childhood
What are the symptoms of congenital HBV?
Asymptomatic
Decompensated cirrhosis
Hepatocellular carcinoma
How is HepA transmitted?
Faecal-oral route
Explain the fate of HepA
Jaundice after a flu-like illness
Does NOT cause chronic liver illness
