CRP/ ESR in Chronic Disease

Question 1

what is CRP

Answer 1

a non specific inflammatory marker made in the liver

Question 2

when is CRP used

Answer 2

in acute inflammation eg:
- burns, trauma, infections, MI, IBD, Cancers, exacerbations of chronic illness

Question 3

what is ESR?

Answer 3

marker of increased fibrinogen
increases number of red blood cells sticking together, so they fall faster

Question 4

what pattern does ESR increase and decrease in

Answer 4

rises and falls slowly

Question 4

which conditions is ESR indicated in?

Answer 4

Malignancies, haematological, connective tissue, infections

Question 5

examples of haematological conditions

Answer 5

multiple myeloma, anaemia of CD,

Question 6

examples of connective tissue conditions

Answer 6

Polymyalgia rheumatica, temporal arteritis, SLE, RAe

Question 7

examples of infections

Answer 7

Acute hep, TB

Question 8

chronic condition management: IBD

Answer 8

CRP is higher in Crohns than in UC

Question 9

chronic condition management: SLE and RA

Answer 9

ESR high in SLE while CRP normal
RA both are high