Creutzfeldt-Jakob Disease

Question 1

What is a prion?

Answer 1

Idiopathic misfolded proteins that can cause neurodegenerative diseases in animals and humans. Don’t contain genetic material.

When a misfolded prion comes into contact with a normal prion can induce adoption of the abnormal shape causing a cascade of misfolding and aggregation.

Question 2

Creutzfeldt-Jakob Disease (CJD) is a rare and fatal neurodegenerative disorder that belongs to a group of prion diseases known as transmissible s_____ e_____

Answer 2

spongiform encephalopathies (TSEs)

Question 3

What are symptoms of Creutzfeldt-Jakob disease (CJD)?

Answer 3

Rapidly progressive dementia
Behavioural changes
Movement abnormalities

Question 4

How quickly does Creutzfeldt-Jakob disease develop?

Answer 4

Quickly, leading to severe disability and death usually within months to a few years after symptoms onset.

Question 5

What is another name for Mad Cow Disease?

Answer 5

Bovine Spongiform Encephalopathy (BSE)

Question 6

Mad Cow Disease is a variant of what other disease?

Answer 6

Creutzfeldt-Jakob Disease

Question 7

What is the treatment for Creutzfeldt-Jakob Disease?

Answer 7

There isn’t one
Relieve symptoms, painkillers
Antidepressants to help with anxiety and depression
Muscle jerks can be treated with sodium valproate