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Pharm Block 2 > Corticosteroids > Flashcards

Corticosteroids Flashcards

1
Q

Alimentary canal mucosal protection

A

PGE2

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2
Q

Maintenance of renal blood flow and sodium excretion in low volume or low output state

A

PGE2

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3
Q

Regulation of platelet function

A

PGI2 and TXA2

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4
Q

Oxytocin and pregnant uterus

A

PGE2 and PGF2a

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5
Q

Vasodilation

A

PGE2, D2

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6
Q

Vascular permeability

A

PGE2, LTs

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7
Q

Hyperalgesia

A

All PGs

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8
Q

Chemotaxis

A

5-HETE and LTB4

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9
Q

Mobilization of bone Ca

A

PGE2 and PGI2

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10
Q

Neutrophil activation

A

LTs

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11
Q

Destabilization of basophils

A

PGD2

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12
Q

Hypothalamic action to elevate normal body temp

A

PGE2

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13
Q

Bronchoconstriction

A

PGD2, PGF2a, SRS-A

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14
Q

Dysmenorrhea, contraction of uterine smooth muscle and vasculature

A

PGF2a

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15
Q

Short-acting steroids

A

Cortisone

Hydrocortisone

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16
Q

Intermediate-acting steroids

A

Prednisone
Prednisolone
Triamcinilone
Methylprednisolone

17
Q

Long-acting steroids

A

Dexamethasone

Bethamethasone

18
Q

Steroids adverse effects

A
  1. Decreased Resistance to infection
  2. Cataracts, Glaucoma
  3. Electrolyte imbalance
  4. Peptic ulcers
  5. Adrenal suppression*
  6. Loss of muscle mass
  7. Osteoporosis*
  8. Delayed Wound healing*
  9. Hyperglycemia*
  10. headoffemur necrosis
  11. Incr. triglycerides
  12. redistributed bodyfat
  13. Diurnal rhythm upset*
  14. Others

Pharm Block 2 (13 decks)

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