Anti-arrhythmics on EKG Flashcards
1
Q
Class 1A (Procainamide, Quinidine)
A
Blocks Na influx Incr. QRS, threshold Decr. conduction Blocks K efflux Incr. QT, refractory
2
Q
Class 1B (Lidocaine)
A
Blocks Na influx in the fast heart
Incr. QRS
Decr. conduction phase 0
3
Q
Class 1C (Flecainide)
A
Tonic block of Na influx
Incr. PR, QRS, threshold
Tonic block of K efflux
Incr. QT, refractory
4
Q
Class 2 (Propranolol, esmolol)
A
Block funny Na current (true beta block)
Block K efflux
Incr. refractory
Block Ca influx
All Incr. PR (phase 4) and Decr. HR
5
Q
Class 3 (Amiodorone)
A
Blocks Betas, Ca incr. PR decr. HR Block Na influx Incr. QRS, threshold Block K efflux Incr. QT
6
Q
Class 3 (Sotolol)
A
Blocks Betas (Na funny)
Decr. HR
Blocks K efflux
Incr. QT, refractory
7
Q
Class 3 (Ibutilide, Dofetilide)
A
Blocks K efflux
Incr. QT
8
Q
Class 4 (Verapamil, Diltiazem)
A
Block Ca Influx Incr. PR Decr. HR (or Incr dep. on BP) Blocks K efflux Incr. refractory
