Coronary heart disease

Question 1

What is coronary heart disease?

Answer 1

Mismatch between myocardial oxygen supply and demand

Question 2

What are the risk factors of coronary heart disease?

Answer 2

Atherosclerotic plaque

Question 3

What are the clinical features of angina?

Answer 3

Retrosternal chest pain or pressure (radiate to left arm, neck, jaw, epigastric region, or back)
Dyspnea
Dizziness, palpitations
Autonomic symptoms (e.g., diaphoresis, nausea, vomiting, syncope)

Question 4

What is the difference between stable and unstable angina?

Answer 4

Stable: Symptoms reproducible under physical or mental stress
Unstable: Angina at rest, usually not relieved by rest or nitroglycerin

Question 5

How is coronary heart disease diagnosed?

Answer 5

(Patient history)
(Resting ECG)
(Cardiac stress test) Physical or Chemical (using adenosine or dobutamine)
Coronary angiography

Question 6

What is the treatment for coronary heart disease?

Answer 6

(All) Risk factor reduction and anti-platelet drugs (i.e. aspirin or clopidogrel)
(Meds) Beta-blockers, nitrates, calcium channel blockers,
(Revascularization)