coronary arteries Flashcards
define coronary vascular reserve
what condition diminishes this
The capacity of the coronary circulation to increase blood flow, The maximum increase in blood flow above the normal resting volume, determines how much you can increase the delivery to get more o2
since the heart already extractrs like all the o2 the only way to increase o2 extraction is to increase flow
diminished by stenosis- arteries already dialated so cant respond to increased demand
what are the ways to influence increased coronary reserve
local dialators: adenosine
endothelium: shear stress –> prostacyclin, NO, EDHF to go to VSMC
nervous: increases vasoconstri BUT the impact on HR and contractility overrides for an overall vasodilation
what artery supplies the SA node
RCA in 60% of cases
what supples the RV
right marginal from RCA, PDA, some of LAD (anterior)
what supples the LV
LCA and PDA
what does the PDA supply
RV, LV, posterior 1/3 of interventricular septum…. anatomizes with left and determines dominance of the heartàbranches of RCA in 67% of people
what does the LCx supply
LA and LV
what supplies the majority of the anterior septum
septal branch of the LAD
what are the most common sites of occlusion
- Proximal LAD, 40-50% of all occlusions
- Proximal RCA*, 30-40% of occlusions
- LCx, 15-20% of occlusions
- LMCA
- Proximal PDA
- RCA distal to marginal a.
where does the coronary sinus drain into
The coronary sinus opening is in the right atrium superior to the septal leaflet of the tricuspid valve. This opening is guarded by the Thebesian valve. Most of the cardiac veins drain into the coronary sinus.
what does the great cardiac vein run with
middle
small
LAD
PDA
right marginal
what two veins The following two veins drain directly into the heart. They do not drain into the coronary sinus.
•Anteriorcardiacveindrains the anterior RV and drain directly into the RA.
Venaecordisminimae(“smallest cardiac veins”, see above) also drain directly into the four chambers of the heart. They are found on both the heart’s anterior and posterior surfaces
what is the difference between the R and L vagus nerve
R- SA
L- AV
differentiate preganglionic and post ganglionic
•Sympathetic motor
- Preganglionicsoriginate in the intermediolateral columns at spinal levels T1 to T4/5. Some travel up to the cervical ganglia
- Postganglionicsdeliver signals to the SA and AV nodes, atrial and ventricular cardiomyocytes, and coronary vessels
•The preganglionic sympatheticssynapse in the cardiac plexus on the way to the heart; the parasympatheticstravel through the cardiac plexus without synapsing.
what is the nerve responsible for cardiac referred pain
ntercostobrachial nerve