Contraception Flashcards

1
Q

Coil use as emergency contraceptive

A

within 5 days of unprotected sexual intercourse.

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2
Q

Contraindications coil

A
Pelvic inflammatory disease or infection
Immunosuppression
Pregnancy
Unexplained bleeding
Pelvic cancer
Uterine cavity distortion (e.g. by fibroids)
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3
Q

Copper coil MOA

A

Copper is toxic to the ovum and sperm.
alters the endometrium and makes it less accepting of implantation.
works by causing cervical mucus to be thicker in consistency and alters motility within the uterotubal system

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4
Q

copper coil Benefits

A

Reliable contraception
It can be inserted at any time in the menstrual cycle and is effective immediately
It contains no hormones, so it is safe for women at risk of VTE or with a history of hormone-related cancers
It may reduce the risk of endometrial and cervical cancer

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5
Q

Copper coil drawbacks

A

A procedure is required to insert and remove
can cause heavy or intermenstrual bleeding
does not protect against sti
Some women experience pelvic pain
increases ectopic pregnancy risk
contraindicated in Wilson’s disease

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6
Q

Levonorgestrel Intrauterine System MOA

A

Thickening cervical mucus
Altering the endometrium and making it less accepting of implantation
Inhibiting ovulation in a small number of women

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7
Q

The Mirena coil is commonly used for

A

contraception, menorrhagia and endometrial protection for women on HRT.
It is licensed for 5 years for contraception, but only 4 years for HRT.

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8
Q

LNG-IUS insertion

A

inserted up to day 7 of the menstrual cycle without any need for additional contraception. If it is inserted after day 7, pregnancy needs to be reasonably excluded, and extra protection (i.e. condoms) is required for 7 days.

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9
Q

LNG-IUS benefits

A

It can make periods lighter or stop altogether
may improve dysmenorrhoea or pelvic pain related to endometriosis

It may improve dysmenorrhoea or pelvic pain related to endometriosis

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10
Q

LNG-IUS drawbacks

A
procedure 
can cause spotting or irregular bleeding
Some women experience pelvic pain
It does not protect against sexually transmitted infections
Increased risk of ectopic pregnancies
Increased incidence of ovarian cysts
There can be systemic absorption causing side effects of acne, headaches, or breast tenderness
can fall out
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11
Q

combined oral contraceptive pill MOA

A
Preventing ovulation (this is the primary mechanism of action)
Progesterone thickens the cervical mucus (reducing chance of semen entering uterus)
Progesterone inhibits proliferation of the endometrium, reducing the chance of successful implantation
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12
Q

Advantages of combined oral contraceptive pill

A

highly effective (failure rate < 1 per 100 woman years)
doesn’t interfere with sex
Times bleeding
contraceptive effects reversible upon stopping
usually makes periods regular, lighter and less painful
reduced risk of ovarian, endometrial - this effect may last for several decades after cessation
reduced risk of colorectal cancer
may protect against pelvic inflammatory disease
may reduce ovarian cysts
May reduce benign breast disease
May reduce acne vulgaris
Improved Perimenopausal Symptoms
Protection from Osteoporosis

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13
Q

Disadvantages of combined oral contraceptive pill

A

people may forget to take it
offers no protection against sexually transmitted infections
increased risk of venous thromboembolic disease
increased risk of breast and cervical cancer, returning to normal ten years after stopping
increased risk of stroke and ischaemic heart disease (especially in smokers)
temporary side-effects such as headache, nausea, breast tenderness may be seen
Mood changes and depression

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14
Q

specific risk factors that should make you avoid the combined contraceptive pill (UKMEC 4):

A

Uncontrolled hypertension (particularly ≥160 / ≥100)
Migraine with aura (risk of stroke)
History of VTE
Aged over 35 and smoking more than 15 cigarettes per day
Major surgery with prolonged immobility
Vascular disease or stroke
Ischaemic heart disease, cardiomyopathy or atrial fibrillation
Liver cirrhosis and liver tumours
Systemic lupus erythematosus (SLE) and antiphospholipid syndrome

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15
Q

Starting the OCP pill

A

Start on the first day of the cycle (first day of the menstrual period). This offers protection straight away. No additional contraception is required if the pill is started up to day 5 of the menstrual cycle.

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16
Q

UKMEC 4 criteria for the Progesterone only pill

A

active breast cancer.

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17
Q

Missing more than one OCP pill (more than 72 hours since the last pill was taken)

A

Take the most recent missed pill as soon as possible
Additional contraception (i.e. condoms) is needed until they have taken the pill regularly for 7 days straight
If day 1 – 7 of the packet they need emergency contraception if they have had unprotected sex
If day 8 – 14 of the pack (and day 1 – 7 was fully compliant) then no emergency contraception is required
If day 15 – 21 of the pack (and day 1 – 14 was fully compliant) then no emergency contraception is needed. They should go back-to-back with their next pack of pills and skip the pill-free period

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18
Q

traditional progestogen-only pill cannot be delayed by more than

A

3 hours. Taking the pill more than 3 hours late is considered a “missed pill”.

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19
Q

desogestrel-only pill can be taken up to

A

12 hours late and still be effective. Taking the pill more than 12 hours late is considered a “missed pill”.

20
Q

Traditional progestogen-only pills work mainly by:

A

Thickening the cervical mucus
Altering the endometrium and making it less accepting of implantation
Reducing ciliary action in the fallopian tubes

21
Q

Desogestrel works mainly by:

A

Inhibiting ovulation
Thickening the cervical mucus
Altering the endometrium
Reducing ciliary action in the fallopian tubes

22
Q

Starting POP

A

Starting the POP on day 1 to 5 of the menstrual cycle means the woman is protected immediately.
It can be started at other times of the cycle provided pregnancy can be excluded. Additional contraception is required for 48 hours. It takes 48 hours for the cervical mucus to thicken enough to prevent sperm entering the uterus

23
Q

Side Effects progesterone only pill

A
Approximately:
20% have no bleeding (amenorrhoea)
40% have regular bleeding
40% have irregular, prolonged or troublesome bleeding
Other side effects include:
Breast tenderness
Headaches
Acne
24
Q

progesterone only pills have an increased risk of:

A

Ovarian cysts
Small risk of ectopic pregnancy with traditional POPs (not desogestrel) due to reduce ciliary action in the tubes
Minimal increased risk of breast cancer, returning to normal ten years after stopping

25
Q

Progestogen only injection fertility

A

can take 12 months for fertility to return after stopping the injections

26
Q

Progestogen only injection

UKMEC

A

UK MEC 4
Active breast cancer

UK MEC 3
Ischaemic heart disease and stroke
Unexplained vaginal bleeding
Severe liver cirrhosis
Liver cancer
27
Q

Side Effects progestogen injection

A
Changes to the bleeding schedule
Weight gain
Acne
Reduced libido
Mood changes
Headaches
Flushes
Hair loss (alopecia)
Skin reactions at injection sites
DMPA can cause osteoporosis.
28
Q

MOA progestogen injection

A

inhibit ovulation. It does this by inhibiting FSH secretion by the pituitary gland, preventing the development of follicles in the ovaries.
Additionally, the depot injection works by:
Thickening cervical mucus
Altering the endometrium and making it less accepting of implantation

29
Q

Timing the Injection

A

Starting on day 1 to 5 of the menstrual cycle offers immediate protection, and no extra contraception is required.
Starting after day 5 of the menstrual cycle requires seven days of extra contraception (e.g. condoms) before the injection becomes reliably effective.
Same applies to progestogen implant

30
Q

Potential Benefits progestogen injection

A
Improves dysmenorrhoea (painful periods)
Improves endometriosis-related symptoms
Reduces the risk of ovarian and endometrial cancer
Reduces the severity of sickle cell crisis in patients with sickle cell anaemia
31
Q

Progestogen only impant

A

slowly releases progestogen into the systemic circulation. It lasts for three years
eg, Nexplanon is licensed for use between the ages of 18 and 40 y
The only UKMEC 4 criteria for the implant is active breast cancer.

32
Q

MOA progestogen only implant

A

Inhibiting ovulation
Thickening cervical mucus
Altering the endometrium and making it less accepting of implantation

33
Q

progestogen only implant timing

A

Inserting the implant on day 1 to 5 of the menstrual cycle provides immediate protection. Insertion after day 5 of the menstrual cycle requires seven days of extra contraception (e.g. condoms), similar to the injection

34
Q

Behavioral contraception

A

Basal body temp - rises following ovulation in response to high progesterone levels
Cervical mucus- thick after menstruation

35
Q

Levonorgestrel should be taken within x hours of UPSI

A

72

36
Q

Ulipristal (ellaone) should be taken within x hours of UPSI

A

120

37
Q

Starting contraception after UPSI levonorgestrel

A

The combined pill or progestogen-only pill can be started immediately after taking levonorgestrel. Extra contraception (i.e. condoms) is required for the first 7 days of the combined pill or the first 2 days of the progestogen-only pill.

38
Q

MOA Ulipristal acetate (Ellaone)

A

selective progesterone receptor modulator (SERM) that works by delaying ovulation. The common brand name is EllaOne. It is more effective than levonorgestrel.

39
Q

Starting contraception after UPSI ulipristal

A

Wait 5 days before starting the combined pill or progestogen-only pill after taking ulipristal. Extra contraception (ie. condoms) is required for the first 7 days of the combined pill or the first 2 days of the progestogen-only pill.

40
Q

restrictions with ulipristal (ellaone):

A

Breastfeeding should be avoided for 1 week after taking ulipristal (milk should be expressed and discarded)
Ulipristal should be avoided in patients with severe asthma

41
Q

After the last period, contraception is required for

A

2 years in women under 50 and 1 year in women over 50

42
Q

Contraception after Childbirth

A

Fertility is not considered to return until 21 days after giving birth
After 21 days women are considered fertile, and will need contraception (including condoms for 7 days when starting the combined pill or 2 days for the progesterone only pill).
Lactational amenorrhea is over 98% effective as contraception for up to 6 months after birth.
progestogen-only pill and implant are considered safe in breastfeeding and can be started at any time after birth.
The combined contraceptive pill should be avoided in breastfeeding
A copper coil or intrauterine system (e.g. Mirena) can be inserted either within 48 hours of birth or more than 4 weeks after birth

43
Q

UK Medical Eligibility Criteria

A

UKMEC 1: No restriction in use (minimal risk)
UKMEC 2: Benefits generally outweigh the risks
UKMEC 3: Risks generally outweigh the benefits
UKMEC 4: Unacceptable risk (typically this means the method is contraindicated)

44
Q

Absolute Contraindications to OCP Contraception (UKMEC 4)

A

Known or suspected pregnancy
smoker over the age of 35 who smokes >15 cigarettes
obesity
breast feeding <6 weeks post partum
Fx of thrombosis before 45 years old
breast cancer or cancer within last few years
BRCA genes

45
Q

OCP Disadvantages of a contraceptive outweigh the advantages (UKMEC 3)

A

Breast feeding >6weeks post partum
Previous arterial or venous clots
continued use after heart disease or stroke
migraines with aura
active disease of liver or gallbladder