Connective Tissue, Olinger Flashcards

1
Q

Embryological connective tissue

A

present as “wharton’s jelly” in umbilical cord

pulp of developing teeth

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2
Q

Histologically distinguishing markers of embryonic CT

A

rich undifferentiated mesenchymal cells

SOME but not much collagen or reticular fibers

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3
Q

Undifferentiated mesenchymal cells differentiate into

A

amy blood or connective tissue cell

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4
Q

Loose (areolar) connective tissue

A

Adult connective tissue

found in mucosa/submucosa of various organs, surrounding blood vessels, nerves and muscles

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5
Q

Tunical Adventitia

A

made up of loose connective tissue

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6
Q

Loose (areolar) connective tissue composition

A

collagen fibers, elastic fibers, mast cells, ground substance

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7
Q

Dense Regular connective tissue is found in

A

tendons, ligaments, cornea and fascia

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8
Q

Dense regular CT consists of……

A

regularly oriented parallel bundles of collagen fibers
separated by linear rows of fibrocytes

the nuclei of the fibrocytes appear linear and the cytoplasm is very difficult to see

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9
Q

Dense irregular connective tissue is found in the…..

A

dermis layer of the skin and submucosa of the GI tract

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10
Q

Dense irregular connective tissue contains

A

course thick, intertwined bundles of collagen fibers arranged irregularly

fibroblasts are sparsely separated: fibroblasts are sparse separated by collagen

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11
Q

two kinds of dense irregular connective tissue

A

reticular connective tissue and elastic connective tissue

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12
Q

reticular connective tissue

A

characterized by abundance of reticular fibers

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13
Q

reticular fibers are produced by

A

fibroblasts, recticulocytes

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14
Q

Elastic connective tissue

A

characterized by an abundance of elastic fibers

elastic fibers of blood vessels are produced by smooth muscle cells

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15
Q

what do elastic fibers form around a lumen

A

discontinuous lamellae

elastic fibers are produced by smooth muscle cells

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16
Q

where are elastic connective tissues typically found?

A

in walls of large blood vessels and ligaments

17
Q

White fat

A

“special connective tissue”

made up of unilocular adipocytes
acts as a reserve of long term energy

18
Q

Brown fat

A

special connective tissue

serves primarily to dissipate energy

made up of multiocular adipocytes

19
Q

between white and brown fat cells, which has the single largest inclusion that pushes the nucleus to an eccentric position

A

white fat

20
Q

what makes brown fat brown?

A

high density of mitochondria and lipid deposits

21
Q

what is an adipocyte exactly?

another name for them.

A

a modified fibroblast. stores lipid in its single unilocular vacuole

sometimes called “signet rings” based on resemblance to a ring

22
Q

how many adipocytes do fat people have compared to skinny people

A

the same, it’s the amount stored in them

23
Q

Cellular make up of connective tissue

A

fibroblasts, macrophages, mast cells, plasma cells

24
Q

Fibroblasts: description (3)

A

spindle shaped cell + oval nucleus

cytoplasm does not show up

25
Q

Type I collagen

A

bone, dentin, tendon

26
Q

Type II collagen

A

Hyaline and elastic cartilage

27
Q

Type III collagen

A

in the reticular lamina of basement membranes

28
Q

Type IV collagen

A

non fibrillous, basement membranes

does not form bundles

29
Q

Type V collagen

A

Umbilicus, chorion, muscle and tendon sheaths

30
Q

Elastic fibers are produced by ____ in skin and tendons, _____ in elastic cartilage, ___ in blood vessels and respiratory tract

A

1) fibroblasts
2) chondroblasts
3) smooth muscle cells

31
Q

Elastic fibers are made from

A

elastin and fibrillin

32
Q

Elastic fibers typically stain

A

dark blue or black

33
Q

Mast cells exist as either _____ or as _______

A

mucosal mast cells in the intestine and lung, or connective tissue mast cells

34
Q

Plasma cells have a _______ looking nucleus based on the the

A

cartwheel looking nucleus bsed on the distribution of heterochromatin

35
Q

which cell has a well developed rER, Golgi, and nucleolus?

A

plasma cells

36
Q

ECM: components

A

proteoglycans, glycosaminoglycans, water, aggregates, hyaluron, and adhesive proteins

37
Q

adhesive proteins in the ECM

A

laminin, fibronectin, integrins