CONNECTIVE TISSUE Flashcards
Holds organs together ``
Connective tissue
Major constituent of Connective tissue is
Extracellular Matrix
Cellular and extracellular component of Connecive tissue
Blood Vessel
ECM
Resident cells
ECM contains
Protein fibers
- Elastic fiber
- Collagen fiver
- reticular fiber
Ground substamce
Residents cells
Mesenchymal cells
Macrophage
Adiposite
Fibroblast
Interstitial fluid in CT gives
metabolic support to cell as the medium for difussion of nutrients and waste products
Connective tissue originates from
Embryonic mesenchyme
Embryonic mesenchyme is tissue developing mainly from the middle layer of embreyo called
Mesoderm
Gives rise to CT
Embryonic mesenchyme
It synthesize and secrets collagen, elastin and substances that makes up ground substance
Fibloblast
substances that makes up ground substance
Gags, proteoglycan and multi adhesive glycoprotein
Serves as medium of difussion of nutrients to all other tissues
Fibloblast
aside from ct itself, this originates locally from mesenchymal cells
Fibloblast
Permanent residents of Connective tissue
Fibloblast
Most common cell in CT, produce and maintain most of tissues extracellular components
Fibloblast
active cells
Fibroblast
quiescent cell
fibrocyte
Fat cells
Adipocytes
found in may organs
Adipocytes
Adipocytes store lipid in a form of neutral fat in the the form of
Triglycerides
Purpose of adiposites
Storage of fat/energy
heat production and insulation
It has phagocytic abiity
Macrophage
Engulf foreign bodies dead cells and etc.
Macrophage
If there is a foreign body, macrophage will engulf it and present it to
Lymphocytes so that lymphocyte will produce antibody and elicit immune response
If a macrophage is present in CT it is called
Histiocytes
Has well developed phagocytic ability and specialize in turnover of protein fibers and removal of dead cells and other materials
Macrophage
Key component of immune response
Macrophage
Antigen presenting cells
Macrophage
Differentiated cells
Mature
undifferentiated cells
immature
Macrophages derived from
bone marrow precursor cells that devide, producing monocytes that circulates in blood. These cells cross epithelial wall of venules to penetrate CT, where they differentiate further, mature and acquire morphologic features of Phagocytic cells.
Mast cells granules provide
Matachromasia. which means they can change the color of basic dyes.
Mast cells contains
Basophilic secretory granules
Basophilic secretory granules serve to
function to loacal inflammatory response, innate immunity and tissue repair.
Basophilic secretory granules
Heparin Histamine Serene proteases Eosinophil and neutrophil chemotactic factors Cytokines Phospholipids