CONNECTIVE TISSUE Flashcards

1
Q

Holds organs together ``

A

Connective tissue

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2
Q

Major constituent of Connective tissue is

A

Extracellular Matrix

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3
Q

Cellular and extracellular component of Connecive tissue

A

Blood Vessel
ECM
Resident cells

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4
Q

ECM contains

A

Protein fibers

  • Elastic fiber
  • Collagen fiver
  • reticular fiber

Ground substamce

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5
Q

Residents cells

A

Mesenchymal cells
Macrophage
Adiposite
Fibroblast

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6
Q

Interstitial fluid in CT gives

A

metabolic support to cell as the medium for difussion of nutrients and waste products

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7
Q

Connective tissue originates from

A

Embryonic mesenchyme

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8
Q

Embryonic mesenchyme is tissue developing mainly from the middle layer of embreyo called

A

Mesoderm

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9
Q

Gives rise to CT

A

Embryonic mesenchyme

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10
Q

It synthesize and secrets collagen, elastin and substances that makes up ground substance

A

Fibloblast

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11
Q

substances that makes up ground substance

A

Gags, proteoglycan and multi adhesive glycoprotein

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12
Q

Serves as medium of difussion of nutrients to all other tissues

A

Fibloblast

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13
Q

aside from ct itself, this originates locally from mesenchymal cells

A

Fibloblast

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14
Q

Permanent residents of Connective tissue

A

Fibloblast

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15
Q

Most common cell in CT, produce and maintain most of tissues extracellular components

A

Fibloblast

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16
Q

active cells

A

Fibroblast

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17
Q

quiescent cell

A

fibrocyte

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18
Q

Fat cells

A

Adipocytes

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19
Q

found in may organs

A

Adipocytes

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20
Q

Adipocytes store lipid in a form of neutral fat in the the form of

A

Triglycerides

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21
Q

Purpose of adiposites

A

Storage of fat/energy

heat production and insulation

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22
Q

It has phagocytic abiity

A

Macrophage

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23
Q

Engulf foreign bodies dead cells and etc.

A

Macrophage

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24
Q

If there is a foreign body, macrophage will engulf it and present it to

A

Lymphocytes so that lymphocyte will produce antibody and elicit immune response

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25
Q

If a macrophage is present in CT it is called

A

Histiocytes

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26
Q

Has well developed phagocytic ability and specialize in turnover of protein fibers and removal of dead cells and other materials

A

Macrophage

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27
Q

Key component of immune response

A

Macrophage

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28
Q

Antigen presenting cells

A

Macrophage

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29
Q

Differentiated cells

A

Mature

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30
Q

undifferentiated cells

A

immature

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31
Q

Macrophages derived from

A

bone marrow precursor cells that devide, producing monocytes that circulates in blood. These cells cross epithelial wall of venules to penetrate CT, where they differentiate further, mature and acquire morphologic features of Phagocytic cells.

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32
Q

Mast cells granules provide

A

Matachromasia. which means they can change the color of basic dyes.

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33
Q

Mast cells contains

A

Basophilic secretory granules

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34
Q

Basophilic secretory granules serve to

A

function to loacal inflammatory response, innate immunity and tissue repair.

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35
Q

Basophilic secretory granules

A
Heparin
Histamine
Serene proteases
Eosinophil and neutrophil chemotactic factors
Cytokines
Phospholipids
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36
Q

Heparin

A

anticoagulant

37
Q

Histamine

A

provide increased vascular permeability and smooth muscle contraction

38
Q

Serene proteases

A

activate various mediators for inflammation

39
Q

Eosinophil and neutrophil chemotactic factors

A

attracts leukocytes

40
Q

Cytokines

A

direct activities of leukocytes and other cells of immune system

41
Q

Phospholipids

A

precursor for conversion of prostaglandins, leukotrienes, and other lipid mediators of the inflammatory response.

42
Q

Sceretes antibodies/immunoglobulin

A

Plasma Cells

43
Q

B-lymphocytes derived

A

Plasma Cells

44
Q

Part of humoral immunity-antibodies

A

Plasma Cells

45
Q

appearance of plasma cells

A

clockface/cartwheel

46
Q

came from blood/napadaan lang

A

Transcient cells

47
Q

transcient cells came from blood and migrate to venules to CT by the process called

A

Diapedesis

48
Q

called by mast cells through chemotactic factor

A

leukocytes

49
Q

hold our body

tensile strength

A

collagen fiber

50
Q

stretches

resiliency

A

elastic fiber

51
Q

very fine/delicate

structural framework

A

reticular fiber

52
Q

makes up population of wondering cells

A

leukocytes

53
Q

extremely strong and resilient

A

collagen fiber

54
Q

most abundant protein in human body

A

Collagen fiber

55
Q

what type of collagen in reticular fiber

A

Type III collagen

56
Q

forms reticulum and extremely thin heavily glycocylated fibers

A

Type III collagen

57
Q

agyrophilic

A

reticulat fiber

58
Q

thinner than type I collagen

A

Elastic fiber

59
Q

only seen in blood vessels

A

Elastic fiber

60
Q

fills spaces between cells and fibers in CT

A

Ground substance

61
Q

Gags also known as

A

mucopolysaccharides

62
Q

gags can be

A

Uronic acis and Hexosamine

63
Q

unoric acid

A

Glunoric acid and iduronic acid

64
Q

hexosamine

A

glucosamine and galactosamine

65
Q

composed of core protein which are conveniently attached to various no./combination of gags

A

proteogylcans

66
Q

milti adhesive glycoprotein

A

laminin and fibronectin

67
Q

for adhesion

A

laminin

68
Q

from insoluble fibral netwrok althroughout CT.

A

fibronectin

69
Q

TYPES OF CT

A

Loose CT

Dense CT

70
Q

areolar tisse

A

loose CT

71
Q

regular/irreg

A

Dense CT

72
Q

common and generally support epithelial tissue

A

Loose CT

73
Q

flexible/not very resistant to stress

A

Loose CT

74
Q

more ground substance/cells

A

Loose CT

75
Q

has more fiber

A

Dense CT

76
Q

adapted to offer stress resistance and protection

A

Dense CT

77
Q

has fewer cells

A

Dense CT

78
Q

bundle of collagen fibers that appear randomly interwoven

A

Dense irregular CT

79
Q

arranged in a defined pattern with fiber

A

Dense rregular CT

80
Q

Consist of ground substance with fewer colagen fiber

A

embreyonic mesenchyme

81
Q

source of multipotent stemcells

A

embreyonic mesenchyme

82
Q

undifferentiated and have large nuclei with prominent nucleus and fine chromatin

A

embreyonic mesenchyme

83
Q

embreyonic type of CT

A

mucoid tissue

84
Q

Found in umbilical chord and fetal organs

A

mucoid tissue

85
Q

abundant ground substance and composed of hyalunoric acid

A

mucoid tissue

86
Q

jellylike with sparse collagen fiber and scattered fibroblast

A

mucoid tissue

87
Q

mucoid tissue is principal component of

A

wartons jelly

88
Q

reticular tissue is produced by

A

modified fibroblast called reticular cell

89
Q

reticular tissue seen in

A

bone marrow, lymph nodes and spleen