CARTILLAGE Flashcards
BONE-MUSCLE
TENDON
BONE TO BONE
LIGAMENT
Tough and felixble form of connective tissue
Cartilage
cartilage is characterized by
ECM with high concentration of GAGs and proteoglycans which interacts with collagen and elastic fibers.
what allows the tissue to bear mechanical stresses without permanent distortion.
ECM
guides development and growth of long bone after birth
Cartilage
avascular
Cartilage
where does cartilage gets nutrients?
from perichondrium
articular cartilage of joints
synovial fluid
Cartilage is consist of
Chondrocytes embedded in extensive ECM communicates via canal helps maintain ECM
Chondrocytes located in matrix cavities called
lacunae
principal collagen type of cartillage
type III collagen
subjected to pulling forces
type I collagen fiber
fibrocartilage
clean appearance
hyaline cartilage
fibrocartilage appearance
madumi
elastic cartilage appearance
mejo madumi
homogenous and semi transparent
Hyaline cartilage
temporary skeleton
hyaline cartilage
regulate formation of hyalin cartilage
somatotrophin
Matrix of hyaline cartilage is consist of
aggrecan
most abundant proteoglycan
aggrecan
it binds specially to GAGs , collagen type II and integrins mediating the adherens of chondrocytes to ECM.
Chondronectin
Layer of Connective tissue that helps nourish cartilage
perichondrium
sorrounds cartilage
perichondrium
for growth and maintainance of cartilage
perichondrium
the inner layer, progenitor of chondroblasts
Fibroblast
chndroblast
divides and differentiate chondrocytes
same with hyaline but has abundant elastic fiber and type II collagen= yellow color of fresh EC.
elastic cartilage
demonstration of Elastic cartilage requires stains such as
orcein and fuchsin
where can we find elastic cartilage?
the auricle of ear, wall of external auditory canal, eustachian tube, epiglottis, cuneiform cartilage in larynx.
hyaline cartilage plus dense connective tissue
fibrocartilage
where can we find fibrocartilage?
vertebral disk, attachment of certain ligament, pubic symphysis.
what makes the matrix of fibrocartilage more acidophilic/ pinkish in HNE stain?
relative scarcity of proteoglycan