Adipose tissue Flashcards
its cells are found in isolated/small groups within loose/dense connecive tissue, but can occur in large as fats in many body regions and organs.
Adipose tissue
Key component of body’s overall energy metabolism.
adipose tissue
asipose tissue stores energy in a form of
Triglycerides
adipose tissue has very active cells responding to
both neurons and hormonal stimuli
endocrine tissue
Adipose tissue
insulates and cushions organs in place
Adipose tissue
unlike other CT, adipocytes are sorrounded by
a thin external lamina containing type IV collagen
soul source of polypeptide hormone called
Leptin
the hormone leptin is a
satiety factor with target cells in hypothalamus and other organs
hormone made by adipose cells, helps regulate energy by inhibiting hunger
Leptin
leptin oppose the action of
grelin
grelin is a
hunger hormone
Helps regulate apitite under normal condition and participate in regulating the formation of new adipose tissue.
Leptin
increased visceral adipose tissue raises the risk of
diabetes and CVD
increased subcutaneous fat does not
during ____ all unilocular adiposites lose nearly all their fats and become ___ or ______ with only very small lipid droplet
starvations
polyhedral/spindle shaped cells
leptin+reactive protein
preventing brain entry/ leptin can’t go to brain
more grelin production
stomach will loosen up
2 types of adipose tissue
white adipose tissue
brown adipose tissue
white adipose tissue is also called
uninocular adipose
has signet ring appearance
white adipose tissue
most common type, compose of cells that when completely developed, contains 1 very large droplet of witish yellow fat in their cytoplasm.
white adipose tissue
brown adipose tissue also called
multilocular adipose
contains cell with multiple lipid droplets interspersed among abundant mitochondria which gives a darker appearance
brown adipose tissue
adipose tissue also came from
Mesenchymal cells
can be fibroblast or free adipocytes
brown adipose tissue
functions of White adipose tissue`
-Specialize for long term energy storage
Why is white adipose tissue called unilocular?
Because triglycerides are stored in alarge dipid droplet
almost all adipose tissue in adults are
uninocular
benign tumors
lipoma
malignant adipose tumor
liposarcomas
fetal lipoma of brown fat
hybernoma
obesity is caused by
excessive formation of adipose tissue when energy intake exceeds energy expenditure
specialized form of AT.
Brown adipose tissue
brown adipose tissue constitute ____ of newly born body weight.
2-5%
location of brown adipose in baby
back, neck and shoulders
for heat production
Brown adipose tissue
heat production by
non shivering thermogenesis
cells are smaller than WAT and centrally located
Brown adipose tissue
adipocytes of brown fat are
closely packed with each large capillaries
heat production because
mitochondria in their inner membrane much greater level of a transmembrane protein called thermogenin/uncoupling protein 1