Congenital, neonatal and perinatal infection Flashcards

1
Q

What is TORCH?

A

Set of 5 diseases that are the classic congenital infections -toxoplasmosis, OTHER (Syphilis, Parvo, VZV, HIV, HBV) rubella, CMV, Herpes

More notes in obstetrics notes

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2
Q

Management of congenital toxoplasmmosis (paeds)

A

More notes in obsetrics

child -1st line pyreamethamine _ sulfadine
with pred

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3
Q

Management of congenital syphilis(paeds)

A

More notes in obstetrics notes

IM benzathine peniciliin

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4
Q

Management of congenital parvovirus (paeds)

A

More notes in obstetrics notes

Intrauterine -blood transfuse if foetal hydrops
Infant -self limiting

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5
Q

Management of congenital Vzv (paeds)

A

More notes in obstetrics notes

IV acyclovir,
neontatl ophtalmic exam
monitor until 28 day post maternal infect

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6
Q

Management of congenital HIV (paeds)

A

More notes in obstetrics notes

Cord clamped as fast as possible and immediate bath
Zidovuline monotherapy for 2-4w (low risk), or 4w of PEP combination
No breastfeeding
All immunisation
PCR at 6, 12 weeks should have passive IgG until 6m

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7
Q

Management of congerintal Hep B (paeds)

A

More notes in obstetrics notes

Acute maternal -not dangerous
chronic HBV - can lead to IUGR and prematurity

HBV vaxx (for mum and child)
Mother- tenofir dosproxil -breastfeeding FINE
Baby -passive immune through HBV IV and HBV vax 12h after birth
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8
Q

Management of congenital Rubella (paeds)

A

More notes in obstetrics notes

Refer child to feotal medicine and notify HPU
no treatment -support
Cardiac scans and screening tests

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9
Q

Management of congenital CMV (paeds)

A

More notes in obstetrics notes

IV ganciclovir

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10
Q

Management of congenital HSV (paeds)

A

More notes in obstetrics notes

Aciclovir if neonate exposed on delivery

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