Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biochem > Complex Lipid Metabolism > Flashcards

Complex Lipid Metabolism Flashcards

1
Q

Triacylglycerol

A

3 carbon-acyl groups with 3 fatty acid groups (one per a carbon)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Phospholipids

A

2 FA groups, 3 carbons, 1 phosphate group with a polar head group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is unique about cardiolipin?

A

Has 2 phosphate groups with 4 FA groups (total, 2 per a P)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Plasmalogens

A

Synthesized in peroxisomes. Have alkenyl alcohol attached via ether linkage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Sphingomyelin

A

Sphingosine + acyl-CoA+PC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Sphingosine

A

Singaling molecule. Only the anime plus a saturated FA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Glycoshingolipid composition

A

shingosine, FA in amide linkage, 1 or more carb derived structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

2 sources of glycerol-3-phosphate

A

Liver (glycerol) and adipose tissue (dihydroxyacetone phosphate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where is glycerol kinase primarily expressed?

A

Liver and intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

TAGS from liver fate

A

packaged/secreted as VLDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

TAGS from adipose fate

A

stored in lipid droplets of adipocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

TAGs from intestine fate

A

Packaged as chylomircons for circulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What tissue does not synthesize phsopholipids?

A

RBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

From what are all glycerophospholipids derived from?

A

phosphatidic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What type of synthesis is DAG used for?

A

PC and PE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How is phosphatidic acid activate for cardiolipin and PI synthesis?

A

Addition of CTP (into CDP-DAG)

17
Q

Dipalmitoylphophatidylcholine

A

2 palmitic acids. Is an important component of lung surfactant

18
Q

Components of PAF

A

1 alkyl ether, 1 acetylglyercol, 1phosphocholine

19
Q

Cerebroside components

A

ceramide + 1 carb

20
Q

Globoside

A

Ceramide + 2 or more carbs

21
Q

Ganglioside

A

Globoside+ 1 or more sialic acids (aka NANAs)

22
Q

Tay-Sachs

A

Sphingolipidose. Deficient in beta-hexosaminidase. Gm2 accumulation. SS: blindness, seizures, cherry-red macula

23
Q

Gaucher

A

Most common sphinolipidose. deficient in glucocerebrosidase. Glucocerebroside accumulation. Hepatosplenomegaly, long bone osteoporosis, severe neurological signs.

24
Q

Fabry

A

Sphingolipidose. Deficient in alpha-galactosidase A. Accumulation of trihexosylceramide. SS: angiokeratoma, renal damage, x-linked**

25
Q

Krabbe

A

Sphingolipidose. Deficient in galactosylceramidase. Accumulation of galactosylceramide and galactosylsphingosine. SS: infantile onset, peripheral neuropathy, loss of myelin

26
Q

Niemann-Pick

A

Sphingolipidose. Deficient in sphingomyelinase. Accumulation of sphingomyelin. SS: neuropathic/non-neuropathic forms, heptaoslpenomegaly, foamy cells in bone marrow

Biochem (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions