Bioenergetics

Question 1

Anabolic pathways

Answer 1

Endergonic
Consume energy
Synthesizes biomolecules from smaller units

Question 2

Catabolic Pathways

Answer 2

Exergonic
Releases energy
Breaks down biomolecules in to smaller units

Question 3

Gibbs free energy formula

Answer 3

∆G=∆H-T∆S

Question 4

If ∆G is negative…

Answer 4

Reaction will proceed forward, and will be exergonic

Question 5

Is ∆G is +…

Answer 5

Reaction in unfavorable, and will be endergonic

Question 6

Standard vs. biological standard ∆G

Answer 6

Standard is at 1 ATM and pH=0, biological is at pH=7

Question 7

For the ∆Gº’, what if eq is less than 1?

Answer 7

Reaction is endergonic and ∆Gº’ is positive

Question 8

For ∆Gº’, what if Keq is greater than 1?

Answer 8

Reaction is exergonic, and ∆Gº’ is negative

Question 9

Why are carbohydrates more easily accessed than lipids?

Answer 9

Carbs are more oxidized

Question 10

What chemical reaction is energy derived from (general)?

Answer 10

Oxidation of metabolic fuels

Question 11

Parts of ATP synthase

Answer 11

F1 (inside membrane)

F0 (incorporated into the membrane)

Question 12

Why is Mg2+ important to ATP?

Answer 12

Draws electron density from the Os and makes the Ps more negative, thus more easily attacked by H2o

Question 13

Bedaquiline

Answer 13

Inhibits Mycobacterium ATP synthase (TB)

Question 14

Baz-423 therapy

Answer 14

Treatment for systemic lupus erythematosus