common viral/fungal

Question 1

HSV treatment/vaccine

Answer 1

Acyclovir

no vaccine

Question 2

VZV treatment/vaccine

Answer 2

chickenpox/shingle vaccine - both live attenuated

acyclovir

Question 3

CMV treatment/vaccine

Answer 3

antiviroal - ganciclovir

No vaccine, but prevent with CMV-IG

Question 4

Herpes general structure

Answer 4

double strantded DNA
icosahedral capside
glycoprotein rich envelope

Question 5

influenza general structure

Answer 5

RNA virus - segmented genome
lipid envelope
Hemagglutinin H and Neuraminidase N glycoprotein (enter/exit)

Question 6

RSV general structure

Answer 6

ss RNA
Enveloped
F - fusion; G - binding

Question 7

RSV symtpoms

Answer 7

respiratory distress
wheezing/rhonchi
hypoxia
copious secretions

Question 8

Ebola general structure and matrix proteins

Answer 8

Eveloped
(-) ss RNA - replicates in cytoplasm
VP40 - stability
VP24 - escape and immune defense
VP30 - forms neucleocaspid
VP35 - RDRP

Question 9

Ebola symptoms

Answer 9

GI, fever, fatigue/weakness, 3rd spacing, fluid loss/capillary leak, vomitting/diarrhea 5-10L/day

Question 10

RSV prophylaxis

Answer 10

Palivizumab
Palavisumab
1/month IM injection

Question 11

Ebola vaccine

Answer 11

none really
zmapp
favipiravir/brincidofovir - developing

Question 12

Influenza vaccine types

Answer 12

1. INactivated influenza - 6mo +

2. LIve attenutated influenza vaccine - 2-49 healthy people - intranasally = fine mist