Common Dermatological Conditions Flashcards

1
Q

What questions do you focus on in a dermatological history?

A
Childhood complaints
Family history
Other medical history; eg: hay fever
What else have you tried?
What makes it worse?
When did it start?
What did it seem related to?
Are you systemically unwell?
Known allergies
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2
Q

Is there a genetic association in atopic eczema?

A

Yes, there’s a genetic predisposition

Elicit from family history

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3
Q

What is the atopic triad?

A

Asthma
Hay fever
Eczema

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4
Q

What are the clinical features of atopic eczema?

A
Moderate itchiness
Erythematous
Diffuse
Flexural - on thinnest skin
Worse in winter because dry
Worse in summer because of heat
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5
Q

What are the environmental triggers of atopic eczema?

A
Irritants
Allergy
Heat
Infection
Itch-scratch cycle
Stress and anxiety
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6
Q

Where is atopic eczema found on an infant, compared to adults?

A

Often on extensor surfaces, rather than flexural surfaces

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7
Q

What is discoid eczema?

A

Eczema in annular disk-like patches

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8
Q

What does discoid eczema mimic?

A

Psoriasis

Tinea

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9
Q

What does discoid eczema respond to?

A

Potent topical steroids

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10
Q

What is asteatotic eczema?

A

Cobblestoned dry skin

Worse on front of legs of elderly patients

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11
Q

What does asteatotic eczema respond to?

A

Emollients - keeps barrier intact to avoid infections

Topical steroids

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12
Q

What is pompholyx?

A

Vesicular hand (and foot) eczema

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13
Q

What can precipitate pompholyx?

A

Excessive washing

Sweating

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14
Q

How is pompholyx treated?

A

Potent topical steroids

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15
Q

How is pompholyx prevented?

A
Avoidance of
- Detergents
- Soaps
- Irritants
Regular emollients
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16
Q

What is diffuse erythrodermic eczema?

A
Severe eczema - >90% of body surface area
Significant morbidity
Usually infected with Staphylococcus
Can be
- Tachycardic
- Hypotensive
- Septic shock
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17
Q

What is the treatment of diffuse erythrodermic eczema?

A

Hospital admittance
Intense topicals
Systemic immunosuppression

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18
Q

What are the complications of eczema?

A

Bacterial superinfection
Eczema herpeticum
Contact dermatitis

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19
Q

What happens in bacterial superinfection of eczema?

A

Eczematous skin lacks natural antibacterial peptides

Often superinfected with S aureus - produces golden crust

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20
Q

What is the treatment for bacterial superinfection of eczema?

A

Systemic anti-Staph antibiotics

30 mL of bleach in 30-40 L bath > bathe children > can decrease high Staph load

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21
Q

What is eczema herpeticum?

A

Secondary infection by HSV pf eczematous skin

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22
Q

What are the clinical features of eczema herpeticum?

A
Dermatomal pattern
Intensely painful vesicles
Sudden onset
Worsening of pre-existing eczema
Punched out erosions
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23
Q

Why is eczema herpeticum an emergency?

A

Risk of corneal scarring

Needs urgent assessment by ophthalmologist

24
Q

What is the treatment for eczema herpeticum?

A

Systemic antiviral treatment

25
What is the difference between allergic and irritant contant dermatitis?
``` Allergic = your own immune system reacting to a substance Irritant = affects everyone; eg: dipping your hands in hydrochloric acid ```
26
What is used to diagnose allergic contact dermatitis?
Patch testing
27
What are the general measures for the treatment of atopic eczema?
Avoid soap Regular emollient Warm, not hot showers
28
What are the specific treatments for atopic eczema?
Topical steroid to inflamed areas Mild steroid for face/non-steroidal anti-inflammatory creams Treat infection with systemic antibiotics
29
What are the other treatment options for atopic eczema?
Wet dressings Phototherapy with UVB Systemic immunosuppression
30
In whom is psoriasis more common: children or adults?
Adults
31
What is the distribution pattern of psoriasis?
Symmetrical Around joints - Affects joints too
32
What are the clinical features of psoriasis?
``` Genetic predisposition Age of onset - 20s - 50s Extensor rash Symmetrical Silvery scale Well demarcated Itchy, but not primary complaint, like in eczema Erythematous/salmon pink ```
33
Describe flexural and genital psoriasis
``` Affects only certain flexural surfaces, like - Under breasts - Around groin - Around gluteal cleft Flatter and less scaly ```
34
Describe palmar-plantar psoriasis
Painful Can develop quite deep fissures Bacterial infections through damaged skin barrier Extreme swelling can lead to infarcts - Grossly swollen hands medical emergencies - Sometimes surgical emergencies
35
What are sterile pustules?
Full of pus, but just part of inflammatory response, not response to infection
36
What is post-streptococcal guttate psoriasis?
1-2 weeks after Streptococcus URTI/tonsillitis Sudden generalised onset of small plaque psoriasis Most will clear with treatment Recurs if Streptococcus infection again
37
What is the treatment for post-streptococcal guttate psoriasis?
Very responsive to phototherapy
38
What is generalised pustular psoriasis?
``` Acute pustular flare of psoriasis Often accompanied by systemic symptoms - Fever - Chills Loss of - Barrier function - Thermoregulation - Protein Risk of - Pre-renal impairment - High output cardiac failure - Sepsis Hospital admission to stabilise ```
39
How do you treat psoriasis?
``` Depends on severity and comorbidities Topical Phototherapy Systemic Often used in combination ```
40
What are the topical treatments of psoriasis?
``` Steroids Tars Calcipotriol Dithranol Keratolytics Emollients ```
41
What are the phototherapy treatments of psoriasis?
Narrowband UVB treatment
42
What are the systemic treatments of psoriasis?
Oral acitretitin Methotrexate Cyclosporin A Biological treatments
43
What are the causes of acne?
``` Starts in adolescence - Increasing sebum production Can be flared by - Hormonal factors - Picking - Emotional stress Medications - Lithium - Anabolic steroids - Topical corticosteroids Topical occlusion - Oily makeup - Moisturisers - Headwear - Hairstyling ```
44
What are the four parts of acne?
Abnormal keratinisation of sebaceous duct Colonisation with Propionobacterium acnes Increase in androgen levels > increased sebum production Inflammation
45
What are blackheads?
Open comedone | - Oxidised sebum
46
What are whiteheads?
Closed comedone
47
What is hormonal acne?
Premenstrual flare | Mainly on lower face
48
What is the treatment of hormonal acne?
Anti-adrogenic OCP +/- anti-androgen
49
What may hormonal acne associated with other features like hirsutism and androgenetic alopecia suggest?
PCOS
50
What is rosacea
2 parts - both can occur at same time/in isolation - Vascular reactivity = redness and flushing - Inflammatory rosacea = papules and pustules
51
What triggers vascular reactivity in rosacea?
``` Sunlight Alcohol Hot foods and drinks Spicy foods Emotion Heat Topical steroids can worsen ```
52
What are the long-term complications of rosacea?
``` Vascular dilatation - Redness - Telangiectasia Tissue hypertrophy - Rhinophyma ```
53
What is the management of rosacea?
``` Avoid triggers Vascular rosacea - Vascular laser Inflammatory rosacea - Topical metronidazole gel - Topical azaleic acid - Systemic antibiotics - Systemic isotretinoin Rhinophyma - Ablative laser - Surgery ```
54
What are the clinical features of scabies?
``` Intensely itchy rash Starts on - Hands - Interdigital spaces - Feet Itch worse at night Spreads to - Genital areas - Generalised body rash Spares face and head in adults Other close contacts develop itch after few weeks ```
55
How is scabies treated?
``` Treat all close contacts at same time - Sexual contacts - Household contacts Index case retreated after 1 week Post-scabies itch takes weeks to settle 5% permethrin Apply cream all over from neck down Leave on overnight Wash off in morning Treat clothing - Hot wash - Tumble dry ```