Coeliac Flashcards
1
Q
Physiol
A
Autoimm resp to peptides from guten prots
Chronic inflamm and villous atrophy
2
Q
Complics
A
Anaemia OP Splenic dysfunction Bact overgrowth CA eg lymphoma
3
Q
px
A
Persis unexpl GI symps Faltering growth Prolonged fatigue Unexpected wl Sev or persis mouth ulcer Iron, B12 or folate defic T1DM AI thyroid dis 1st degree fam hx Osteomalacia or low bone density Periph neurop or ataxia Misc or subfertility High LFTs
4
Q
ix
A
Bloods- IgA tTGA (tissue transglutaminase Ab) and total IgA ist line IgA EMA (endomysial Ab) if above unavail or weakly pos If bloods pos then endosc and biop
5
Q
mx
A
Gluten free diet
