Allergy Mainly Food

Question 1

Allergy defin

Answer 1

Imm hypersens reac that can lead to diff diseases. IgE (peanut) or non IgE med (milk)
Sensitisat is IgE produc is resp to allergen

Question 2

Mediators

Answer 2

Histamine
Tryptase
LTR
Prostaglandin
IL5

Question 3

Ix

Answer 3

Clinical hx and diary, what tried
IgE immunoassay- ELISA, W blot
Skin prick wheal after 15min- IgE immed
Challenge test
Gold stand DBPCFC- double blind placebo controlled food challenge

Question 4

Mx

Answer 4

AVOID
Action plan
Anticip allergy testing due to x reactivity
Dietician
Antihist
Emergency meds maybe
Somet densensitisation, or early food introduction

Question 5

Food allergy hypothesese

Answer 5

Hygeine- lack infec exposure
Dual allergen exposure- early oral expos induces tol, early cutan expos sensitises
Vit D- reguls imm mechs

Question 6

Food allergy

Answer 6

Adverse effect from sepcif imm resp reproducibly on expos to a food.

Question 7

IgE med food

Answer 7

Immed 5-30 min, incl urticaria and angioed
Eg milk, egg, fish, fruit, veg
Variable age but all milk allergy by one yr
Milk and egg can resolve with age

Question 8

non IgE med food

Answer 8

Delayed hrs to days, prim GI symps
Eg milk, soya, wheat, rice, oats
Infancy and early child
Us resolve by school age