Anaphylaxis Flashcards
1
Q
Definition
A
Severe airway/resp and circ compromise. Usually skin and mucosal changes. Acute and life threatening. Over 30% reduc BP or end organ symps. May be persis GI symps.
2
Q
Mediators
A
Histamine
Tryptase
PAF
3
Q
px
A
Skin- itch, erythema, urticaria, angiodema
Resp- stridor, hoarse, tachyp, wheeze, tightness
GI- NV
CVS- hypot, long CRT
Neuro- LOC, GCS under 15
4
Q
Causes
A
Kids- nuts, milk, egg
Adult- insect, drugs, fish, nuts
Sensitised indiv exposed to specif Ag. IgE to Ag to mast and baso to hist to body resp.
5
Q
Acute mx
A
ABCDE, HELP Remove trigger, maint airway, oxygen Adrenaline IM 1/1000 0.01ml/kg. Rep every 5 mins as required. Salbutamol neb for bronchospasm Antihistamine eg IV chlorpheniramine 10mg Hydrocortisone IV 200mg Lie flat and fluids if hypot Neb adrenaline if laryngeal oedema
6
Q
LT mx
A
Avoidance
Immunomodulation
Risk assess
Epipen- remove cap to prime. Orange or black to thigh. Push and hold for 5-10 sec. lie with feet up.
7
Q
Ix
A
High serum tryptase
