Clostridium Flashcards
Morphology
7-10um, rod, all have flagella but perfringens, no capsule, spore can be terminal central or sub terminal.
Environment
Soil mud water and gut
Staining and culture
Gram positive, nutrient and blood agar
Aerobic or anaerobic
Aerotolerant, novyi and tetani aren’t
Temperature
15-22 putrefaciens, 40-45 perfringens, 37 optimal
Tests?
Catalase negative, oxidase negative, fermentative
Disease catagories
Gas gangrenic, enterotoxaemic, intoxication
Gas gangrenic diseases
Malignant odema- septicum, novyi, haemolyticum, histolyticum, sordelli.
Black leg- chauvei
Hu gas gangrene- perfringens A and novyi A
Intoxication diseases
Tetani and botulinum
Enterotoxaemic diseases perfringens A
Necrotic enteritis of chicken,
Hu GG,
necrotising colitis in Su,
Ca haemoragic enterocolitis.
Perfringens B
Lamb dysentery
Haemoragic enteritis in calf and foal
Perfringens C
Necrotising enteritis in pig and chicken
Sheep struck
Perfringens D
Pulpy kidney in sheep
Perfringens E
Haemoragic enteritis in calf
Enteritis in rabbit
Odd enterotoxaemic species?
Colinium- ulcerative chicken enteritis