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cloistridium Flashcards

1
Q

habitat

A

soil, mud, water, gut

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2
Q

morphology

A

big rods, flagellated spore, no capsule

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3
Q

which species isnt flagellated

A

c perfringens

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4
Q

which species is capsulated

A

c perfringens

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5
Q

staining

A

Gr+

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6
Q

culture

A

anaerobic, oxygen tolerance different, nutrient agar, blood agar, optimal temperature 37

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7
Q

strictly anaerobic species

A

c tetani, c novyi

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8
Q

species that can tolerate oxygen

A

c histolyticum, c botulinum

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9
Q

c perfringens optimal temp

A

40-45

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10
Q

c putrefaciens optimal temp

A

15-22

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11
Q

catalase

A

neg

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12
Q

oxidase

A

neg

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13
Q

OF

A

fermentative

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14
Q

biochemistry

A

active, carbs fermentated, proteolytic, exotoxins

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15
Q

proteolytic species

A

tetani, histolyticum, botulinum

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16
Q

which species do not ferment carbohydrates

A

tetani, histolyticum

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17
Q

antigens

A

complex, close relationship

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18
Q

spore resistance in dry specimens

A

for years

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19
Q

c botulinum resistance boiling

A

3-4hrs

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20
Q

perfringens spore resistance boiling

A

5-10mins

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21
Q

perfringens spore resistance formaline

A

2hrs

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22
Q

neurotoxic cloistridia

A

tetani, botulinum

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23
Q

histotoxic cloistridia

A

chauvoei, septicum, novyi A, perfringens A, sordelii, haemolyticum, novyi B

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24
Q

enteropathogenic and enterotoxaemia producing cloistridia

A

perfringens, difficile, colinum, spiroforme

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25
atypical clostridial organism
piliforme
26
pathogenicity
- gas gangrene diseases - enterotoxaemic diseases - intoxications
27
gas gangrenic diseases
- malignant oedema - blackleg - human gas gangrene
28
malignant oedema causing species
septicum, novyi, haemolyticum, histolyticum, sordelii
29
blackleg causing species
chauvoei
30
human gas gangrene causing species
perfringens A, novyi A
31
enterotoxaemic diseases
-necrotic enteritis of chicken -lamb dysentery necrotic enteritis of pig, struck of sheep pulpy kidney disease of sheep ulcerative enteritis of chicken
32
necrotic enteritis of chicken causing species
perfringens A/C
33
lamb dysentery causing species
perfringens B
34
necrotic enteritis of pigs, struck of sheep
perfringens C
35
pulpy kidney disease of sheep
perfringens D
36
ulcerative enteritis of chicken
colinum
37
intoxications
tetanus | botulism
38
c septicum culture
nutrient agar
39
c septicum toxins
alpha, DNAase, hyaluronidase, haemolysin
40
c septicum disease
malignant oedema in cattle, pig and sheep, bradsot
41
c novyi toxins
alpha, lipase, lecitinase, DNAase, collagenase
42
c novyi diseases
gas gangrene, infectious necrotic hepatitis of sheep
43
c haemolyticum disease
bacillary haemoglobinria of cattle
44
c histolyticum habitat
wide spread, can tolerate O2
45
c histolyticum toxins
alpha, collagenase, protease, elastase, haemolysin
46
c histolyticum disease
malignant oedema cattle, pig and sheep
47
c chavoei culture
blood agar, strong haemolysis
48
c chavoei disease
blackleg in cattle and sheep
49
c chavoei differentiation from septicum
-culture immunofluorescence animal trial
50
c chavoei toxins
same as septicum
51
perfringens optimal temp
40-45
52
perfringens morphology
no flagella, capsule
53
perfringens main toxins
alpha, beta, epsilon, iota
54
perfringens auxiliary toxins
gamma, delta, theta, kappa, lambda, mu
55
necrotic enteritis in chickens, human gas gangrene, food infection perfringens toxins
alpha
56
lamb dysentery perfringens toxins
alpha, beta, epsilon
57
necrotic enteritis of pigs, struck, necrotic enteritis in chicken
alpha, beta
58
pulpy kidney disease in sheep
alpha, epsilon
59
enteritis in rabbits perfringens toxins
alpha, iota
60
which perfringens toxins need to be activated by trypsin
epsilon and iota
61
what is struck
an acute, highly fatal enterotoxaemia of sheep
62
colinum affected species
quail, chicken, turkey, pheasant
63
colinum disease
ulcerative entertitis - intestinal ulceration, hepatic necrosis
64
difficile toxins
enterotoxin, cytotoxin
65
difficile human
pseudomembranaceus colitis
66
difficile foal
haemorrhagic enterocolitis in newborn foals
67
difficile dog
chronic diarrhoea
68
piliforme culture
mouse fibroblast, liver, embryonated egg
69
piliforme disease
tyzzers disease
70
how many serotypes of tetani are there
10
71
toxins of c tetani
neurotoxin haemolysin fibrinolysin
72
c tetani disease
tetanus
73
highly susceptible species to tetanus
horse, man
74
moderately susceptible species to tetanus
ruminants and pigs
75
resistant species to tetanus
carnivores, poultry
76
site of production of tetani neurotoxin
in deep anaerobic wounds
77
where are the genes that regulate production of tetani neurotoxin
in plasmids
78
how many antigenic types of tetani neurotoxin
one
79
mode of action of tetani neurotoxin
synaptic inhibition in inhibitory nerve
80
clinical effect of tetani neurotoxin
muscular spasm
81
botulinum toxin types
a,b,c,d,e,f,g
82
abef toxin types botulinum
acativated by trypsin, soil, human disease
83
cd botulinum toxin types
soil, intestine - animal disease
84
site of production of botulinum neurotoxin
in carcasses, decaying vegetation, feedstuff, canned foods, occasionally in wounds or intestine
85
genes which regulate production of botulinum neurotoxin
usually in genome, in bacteriophage for CD
86
how many diff antigen types for botulinum neurotoxin are there
7
87
mode of action botulinum neurotoxin
inhibition of neuromuscular transmission
88
clinical effect botulinum neurotoxin
flaccid paralysis

Bacto (19 decks)

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