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Bacto > cloistridium > Flashcards

cloistridium Flashcards

1
Q

habitat

A

soil, mud, water, gut

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2
Q

morphology

A

big rods, flagellated spore, no capsule

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3
Q

which species isnt flagellated

A

c perfringens

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4
Q

which species is capsulated

A

c perfringens

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5
Q

staining

A

Gr+

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6
Q

culture

A

anaerobic, oxygen tolerance different, nutrient agar, blood agar, optimal temperature 37

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7
Q

strictly anaerobic species

A

c tetani, c novyi

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8
Q

species that can tolerate oxygen

A

c histolyticum, c botulinum

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9
Q

c perfringens optimal temp

A

40-45

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10
Q

c putrefaciens optimal temp

A

15-22

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11
Q

catalase

A

neg

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12
Q

oxidase

A

neg

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13
Q

OF

A

fermentative

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14
Q

biochemistry

A

active, carbs fermentated, proteolytic, exotoxins

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15
Q

proteolytic species

A

tetani, histolyticum, botulinum

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16
Q

which species do not ferment carbohydrates

A

tetani, histolyticum

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17
Q

antigens

A

complex, close relationship

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18
Q

spore resistance in dry specimens

A

for years

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19
Q

c botulinum resistance boiling

A

3-4hrs

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20
Q

perfringens spore resistance boiling

A

5-10mins

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21
Q

perfringens spore resistance formaline

A

2hrs

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22
Q

neurotoxic cloistridia

A

tetani, botulinum

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23
Q

histotoxic cloistridia

A

chauvoei, septicum, novyi A, perfringens A, sordelii, haemolyticum, novyi B

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24
Q

enteropathogenic and enterotoxaemia producing cloistridia

A

perfringens, difficile, colinum, spiroforme

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25
Q

atypical clostridial organism

A

piliforme

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26
Q

pathogenicity

A
  • gas gangrene diseases
  • enterotoxaemic diseases
  • intoxications
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27
Q

gas gangrenic diseases

A
  • malignant oedema
  • blackleg
  • human gas gangrene
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28
Q

malignant oedema causing species

A

septicum, novyi, haemolyticum, histolyticum, sordelii

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29
Q

blackleg causing species

A

chauvoei

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30
Q

human gas gangrene causing species

A

perfringens A, novyi A

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31
Q

enterotoxaemic diseases

A

-necrotic enteritis of chicken
-lamb dysentery
necrotic enteritis of pig, struck of sheep
pulpy kidney disease of sheep
ulcerative enteritis of chicken

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32
Q

necrotic enteritis of chicken causing species

A

perfringens A/C

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33
Q

lamb dysentery causing species

A

perfringens B

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34
Q

necrotic enteritis of pigs, struck of sheep

A

perfringens C

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35
Q

pulpy kidney disease of sheep

A

perfringens D

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36
Q

ulcerative enteritis of chicken

A

colinum

37
Q

intoxications

A

tetanus

botulism

38
Q

c septicum culture

A

nutrient agar

39
Q

c septicum toxins

A

alpha, DNAase, hyaluronidase, haemolysin

40
Q

c septicum disease

A

malignant oedema in cattle, pig and sheep, bradsot

41
Q

c novyi toxins

A

alpha, lipase, lecitinase, DNAase, collagenase

42
Q

c novyi diseases

A

gas gangrene, infectious necrotic hepatitis of sheep

43
Q

c haemolyticum disease

A

bacillary haemoglobinria of cattle

44
Q

c histolyticum habitat

A

wide spread, can tolerate O2

45
Q

c histolyticum toxins

A

alpha, collagenase, protease, elastase, haemolysin

46
Q

c histolyticum disease

A

malignant oedema cattle, pig and sheep

47
Q

c chavoei culture

A

blood agar, strong haemolysis

48
Q

c chavoei disease

A

blackleg in cattle and sheep

49
Q

c chavoei differentiation from septicum

A

-culture
immunofluorescence
animal trial

50
Q

c chavoei toxins

A

same as septicum

51
Q

perfringens optimal temp

A

40-45

52
Q

perfringens morphology

A

no flagella, capsule

53
Q

perfringens main toxins

A

alpha, beta, epsilon, iota

54
Q

perfringens auxiliary toxins

A

gamma, delta, theta, kappa, lambda, mu

55
Q

necrotic enteritis in chickens, human gas gangrene, food infection perfringens toxins

A

alpha

56
Q

lamb dysentery perfringens toxins

A

alpha, beta, epsilon

57
Q

necrotic enteritis of pigs, struck, necrotic enteritis in chicken

A

alpha, beta

58
Q

pulpy kidney disease in sheep

A

alpha, epsilon

59
Q

enteritis in rabbits perfringens toxins

A

alpha, iota

60
Q

which perfringens toxins need to be activated by trypsin

A

epsilon and iota

61
Q

what is struck

A

an acute, highly fatal enterotoxaemia of sheep

62
Q

colinum affected species

A

quail, chicken, turkey, pheasant

63
Q

colinum disease

A

ulcerative entertitis - intestinal ulceration, hepatic necrosis

64
Q

difficile toxins

A

enterotoxin, cytotoxin

65
Q

difficile human

A

pseudomembranaceus colitis

66
Q

difficile foal

A

haemorrhagic enterocolitis in newborn foals

67
Q

difficile dog

A

chronic diarrhoea

68
Q

piliforme culture

A

mouse fibroblast, liver, embryonated egg

69
Q

piliforme disease

A

tyzzers disease

70
Q

how many serotypes of tetani are there

A

10

71
Q

toxins of c tetani

A

neurotoxin
haemolysin
fibrinolysin

72
Q

c tetani disease

A

tetanus

73
Q

highly susceptible species to tetanus

A

horse, man

74
Q

moderately susceptible species to tetanus

A

ruminants and pigs

75
Q

resistant species to tetanus

A

carnivores, poultry

76
Q

site of production of tetani neurotoxin

A

in deep anaerobic wounds

77
Q

where are the genes that regulate production of tetani neurotoxin

A

in plasmids

78
Q

how many antigenic types of tetani neurotoxin

A

one

79
Q

mode of action of tetani neurotoxin

A

synaptic inhibition in inhibitory nerve

80
Q

clinical effect of tetani neurotoxin

A

muscular spasm

81
Q

botulinum toxin types

A

a,b,c,d,e,f,g

82
Q

abef toxin types botulinum

A

acativated by trypsin, soil, human disease

83
Q

cd botulinum toxin types

A

soil, intestine - animal disease

84
Q

site of production of botulinum neurotoxin

A

in carcasses, decaying vegetation, feedstuff, canned foods, occasionally in wounds or intestine

85
Q

genes which regulate production of botulinum neurotoxin

A

usually in genome, in bacteriophage for CD

86
Q

how many diff antigen types for botulinum neurotoxin are there

A

7

87
Q

mode of action botulinum neurotoxin

A

inhibition of neuromuscular transmission

88
Q

clinical effect botulinum neurotoxin

A

flaccid paralysis

Bacto (19 decks)

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