Clinical IBD Flashcards
in which dz is genetics more important? genes?
CD. NOD2
most important evironmental factor
smoking (protective for UC, predisposing for CD)
fistulas seen in which dz
CD
skeletal manifestations of IBD
sacroiliits, AS, peripheral arthropathy, osteopenia/porosis
type 1 vs 2 peripheral arthropathy
type1: <5 joints, large joints, b27
Type 2: polyarticular, small joints
derm manifestations
pyderma gangrenosum, erythema nodosum, cutaneous CD, aphthous ulcres
ocular manifestations
episcleritis, iritis, retinitis
hepatobiliary manifestations
Primary sclerosing cholangitis
pathology in the two dzs
UC: mucosal, no granulomas.
CD: transmural, granulomas
surgery in IBD
curative in UC, not in CD
medical tx
anti-inflammatory: steroids, immunosuppression