Clinical examination and investigation of respiratory disease Flashcards

1
Q

history + signalment

A
Herd or individual problem 
Neonate, juvenile, or adult 
Performance, pleasure, or production 
Management and environment 
Disease time course and features 
Response to treatment
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2
Q

cough description

A

type (non/productive)

frequency

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3
Q

observe from a distance - what to look for

A

general behaviour and demeanour
Respiratory rate, effort and pattern
inspiratory and expiratory noise

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4
Q

general clinical exam

A
Body condition 
Posture 
Abdominal effort 
Hypertrophy of abdominal muscles 
Mucous membranes 
Eyes 
Jugular veins 
Pectoral oedema
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5
Q

specific clinical exam

A

Nares and Nasal Passages
airflow obstruction
Discharges

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6
Q

paranasal sinuses - horse

A

Looking for facial symmetry

Percussion

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7
Q

pharyngeal area

A
Guttural Pouches (Horse) - swelling 
Lymph nodes - enlargement, discharges 
Larynx (Horse) - Asymmetry of cricoarytenoideus dorsalis muscle - Movement in response to slap over withers
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8
Q

Equine Thoracic Auscultation and Percussion

A
Quiet room 
Just audible in adult horse 
Louder in foals and thin animals 
Absence of noise - consolidation 
Radiating heart sounds with pleural effusion
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9
Q

Ruminant Auscultation and Percussion area

A

6th intercostal space - point of the elbow
9th intercostal space - midway
11th - level with the tuber coxae
diaphragmatic border - straight

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10
Q

Auscultation - Small Animals

A

Not a reliable indicator of respiratory disease
Absence of sounds does not imply absence of disease
Usually significant if respiratory noise increased
Beware of referred noise from the URT
Differentiate crackles and wheezes

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11
Q

Auscultation - Small Animals - Crackles

A

likely to indicate small airways and alveoli

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12
Q

Auscultation - Small Animals - Wheezes

A

partial obstruction of larger airways

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13
Q

Apex Beat (SA) - shifting

A

displacement of the heart - probably due to a space occupying lesion

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14
Q

Endoscopy - Equine

A

At rest – standing restrained animal +/- sedation
Exercise – treadmill or dynamic endoscopy
Techiques - Tracheal aspirate, BAL, Biopsy, FB retrieval

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15
Q

endoscopy - equine - what to see

A
Nasal passages 
Guttural pouch 
Nasopharynx 
Soft palate 
Larynx 
Trachea
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16
Q

Endoscopy in Small Animals - what is accessible

A

Trachea
Mainstem bronchi
Larger divisions of main bronchi
Smaller airways not accessible

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17
Q

Endoscopy - Small Animals

A

Patient able to tolerate general anaesthesia
Sufficient diameter of trachea to accommodate the endoscope (> 5mm)
Take radiographs before endoscopy
Artefact following washes
Place patient in sternal recumbency
Examine airways in systematic fashion

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18
Q

endoscopy - small animals - most useful cases

A

Diseases of major airways - Bronchitis, Parasitic bronchitis
Dynamic disease of the upper airway - Tracheal + Bronchial collapse, Consider also fluoroscopy

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19
Q

endoscopy - small animals - weaknessess

A

Unable to visualise smaller airways - Asthma

Unable to visualise parenchymal lesions - Solitary lung masses, Diffuse alveolar disease

20
Q

Techniques Possible via endoscope

A

Aspiration of samples - Tracheal wash, Guided bronchoalveolar lavage, Cytology brushes
Biopsy of discrete lesions
Retrieval of foreign bodies

21
Q

viral infection diagnosis

A

Paired serology
Virus isolation from buffy coat
Virus isolation from nasopharyngeal swabs
Viral antigen detection by FAT or ELISA from nasopharyngeal swabs
PCR to identify RNA/DNA of specific viruses

22
Q

how to obtain Samples for Cytology and/or Bacterial Culture

A
Nasopharyngeal swab 
Guttural pouch lavage (horse) 
Endoscopically guided tracheal aspirate 
Transtracheal aspirate 
Bronchoalveolar lavage 
Pleural fluid 
Lung biopsy
23
Q

Nasopharyngeal Swab

A

bacterial culture of specific organisms that are not normal comensals of the pharynx
e.g. Streptococcus equi equi

24
Q

Guttural Pouch Lavage: Equine

A
Endoscope within GP 
Plastic tubing via biopsy port 
Aspirate mucopurulent discharge 
Lavage both pouches and re-aspirate fluid 
GP has commensal organisms 
Streptococcus equi - Culture, PCR
25
Endoscopically-Guided Tracheal Aspirate: Equine
Position endoscope at thoracic inlet Advance catheter and insert 30 mls sterile (buffered) saline Withdraw sample Post-exercise?
26
Endoscopically-Guided Tracheal Aspirate: Small Animals
General anaesthesia Go via ET tube - Not in cats, pull tube first Blind wash Use plastic tube via ET tube
27
Endoscopically-Guided Tracheal Aspirate - advantages
easy to perform non-invasive sample is representative of the whole lung
28
Endoscopically-Guided Tracheal Aspirate - disadvantages
sample is contaminated by pharygneal flora (horse) sample can be contaminated by equipment wide range in normal cell populations cells poorly preserved
29
Transtracheal Aspirate (Horse) - method
Surgically prepare site in lower third of the trachea Local anaesthetic Insert guide catheter (10 gauge, 3 inch) or needle between tracheal rings Insert sample catheter (16-14 gauge, 30 cm) Insert 25 - 30 mls sterile saline Withdraw sample Remove sample catheter Remove guide catheter last to avoid contamination of subcutaneous tissues
30
Transtracheal Aspirate - advantages
no pharyngeal contamination no specialised equipment useful in young foals where standard endoscopes are too large
31
Transtracheal Aspirate - disadvantages
horse may cough catheter into pharynx and contaminate sample invasive - cellulitis + subcutaneous emphysema
32
Trans-tracheal wash - Small Animals - Indications
Collection of tracheal secretions where endoscopy not available - Anaesthesia contra-indicated Direct access to airway in conscious patient
33
Bronchoalveolar Lavage (Horse)
``` (Insert guide catheter into trachea) Advance BAL tube into bronchus until it will not advance further (Inflate balloon) Insert 120 - 200 mls sterile saline Withdraw sample ```
34
Bronchoalveolar Lavage (Horse) - advantages
sample obtained from the area of tract that is most likely to be affected by e.g. EIPH, COPD narrow range of cell populations aids interpretation equipment cheap and accessible therefore used in all large animal species
35
Bronchoalveolar Lavage (Horse) - disadvantages
site may not be appropriate in animals with localised pulmonary abscesses or pneumonias
36
Thoracocentesis: Equine
Select site in seventh or eight intercostal space, above lateral thoracic vein surgical preparation and local anaesthesia stab incision blunt teat cannula or drain closed from atmosphere
37
Thoracocentesis: Small Animal
Cranial or caudal to heart Site determined by radiography or ultrasound guidance If fluid evenly distributed then rib-spaces 8 or 9 on either side Use local anaesthesia (not in cat) Closed system catheter/needle, fluid extension set, Three way tap, large volume syringe
38
lung aspiration - indications
Where a discrete intrapulmonary abnormality exists or where there is diffuse disease that cannot be accessed in any other way an aspirate of the lung may be appropriate
39
lung aspiration
Use ultrasound or fluoroscopic guidance | Incr morbidity + mortality of unguided aspirates means these are saved for the most seriously ill patients
40
lung biopsy - advantages
not frequently performed used for identification of specific forms of pathology e.g. interstitial pneumonia, neoplasia
41
lung biopsy - disadvantages
very invasive - Thoracotomy/thoracoscopy painful complications include - uncontrollable haemorrhage, pneumothorax
42
faecal exam - small animals
Parasite larvae - Angiostrongylus vasorum
43
Thoracic Radiography
pulmonary pleural cavity mediastinum
44
Computed Tomography (CT) - small animals
Useful for pleural, mediastinal + parenchymal structures. High image quality of detailed sectional anatomical structure. Cheaper and quicker and better detail of lung tissue than MRI Does not require gating for respiration like MRI. Radiation exposure unlikely to be an issue in our patients.
45
Thoracic Ultrasonography
Sound does not penetrate normal aerated lung Sound will penetrate non-aerated (diseased) lung Lesions that do not extend to the surface of the lung are not visible Extremely useful for characterising pleural effusion Can be used to obtain samples - pleurocentesis, lung biopsy etc.
46
pulomary function tests - equine
``` Track exercise tests Treadmill exercise tests Oesophageal manometry Flow-volume loops Oxygen uptake Blood gas analysis ```