Classic/Relevant treatments Flashcards by c k

abscence seizure

ethosuximide

How well did you know this?

Not at all

Perfectly

acute gout attack

NSAIDs, colchicine, glucocorticoids

How well did you know this?

Not at all

Perfectly

acute promyleocytic leukemia (M3) - subtype of aml t(15:17)

All-trans retinoic acid

How well did you know this?

Not at all

Perfectly

ADHD

Methylphenidate, cbt, atomoxetine

How well did you know this?

Not at all

Perfectly

Alcoholism

Disulfiram, amcamprosate, naltrexone, supportive care

How well did you know this?

Not at all

Perfectly

alcohol withdrawal

long acting benzos - chlordiazepoxide, diazepam

How well did you know this?

Not at all

Perfectly

anorexia

nutrition, psychotherapy, mirtazapine (antagonizes inhibitory autoreceptors of serotonin and a-2)

How well did you know this?

Not at all

Perfectly

anticoagulation during preggos

heparin

How well did you know this?

Not at all

Perfectly

arrhythmia in damaged cardiac tissue

Class IB antiarrhythmetics - lidocaine, mexiletine

How well did you know this?

Not at all

Perfectly

B12 deficiency

vitamine b12 supplementation - work up with schilling test

How well did you know this?

Not at all

Perfectly

BPH

alpha-1 antagonists (doxozosin)
5 alpha reductase inhibitors (finasteride, dutasteride)
PED-5 inhibitors (sildinefil)

How well did you know this?

Not at all

Perfectly

Bipolar

lithium, valproic acid, carbamazepine

atypical antipsychotics

How well did you know this?

Not at all

Perfectly

breast cancer in postmenopausal women

aromatase inhibitors (anastrozole)

How well did you know this?

Not at all

Perfectly

buerger disease - disease of arteries and veins in arms and legs - blood vessels become inflamed, swell, and can become blocked with blood clots - can destroy skin and lead to infection or gangrene

smoking cessation

How well did you know this?

Not at all

Perfectly

bulimia nervosa

SSRI

How well did you know this?

Not at all

Perfectly

Candida albicans

topical azoles (vaginitis); nystatin, fluconazole, caspofungin (oral/esophageal); fluconozole, caspofungin, amphotericin B (systemic)

How well did you know this?

Not at all

Perfectly

carcinoid

octreotide

How well did you know this?

Not at all

Perfectly

bleeding esophageal varices

octreotide

How well did you know this?

Not at all

Perfectly

Chlamydia trachomatis

doxycyline (+ceftriaxone for gonorrhea coinfection), erythromycin eye drops (prophylaxis for infants)

How well did you know this?

Not at all

Perfectly

chronic gout

xanthine oxidase inhibitors (allupurinol, febuxostat)

How well did you know this?

Not at all

Perfectly

chronic hep b or c

IFN- alpha (HBV and HCV); ribavirin, simeprevir, sofosbuvir (HCV)

How well did you know this?

Not at all

Perfectly

CML

Imatinib

How well did you know this?

Not at all

Perfectly

Clostridium botulinum

Antitoxin

How well did you know this?

Not at all

Perfectly

Clostridium difficile

Oral metronidazole, if refractory, oral vancomycin

How well did you know this?

Not at all

Perfectly

clostridum tetani

aNTITOXIN

cmv

Ganciclovir, foscarnet, cidofovir

Crohn's disease

corticosteroids, infliximab (monoclonal anti-TNF-alpha...note that the xi tells you it is chimeric), azathioprine (immnunosuppressant - blocks purine synthesis particularly in t and b cells)

cryptococcus neoformans

fluconazole (in AIDS)

Cyclophosphamide induced hemorrhagic cystitis (i.e. toxic metabolites from chemo)

Mesna

depression

SSRI

Diabetes insipidus

Desmopressin (central); hydrochlorothiazide (NaCl DCT), indomethacin (NSAID), amiloride (ENaC CD) (nephrogenic)

DM I

Diet (low carb) + insulin

DM II

Diet, oral hypoglycemics, and insulin if refractory

DKA

Fluids, insulin, K+

Enterococci

vanco, aminopenicillin/cephalosporins

Sildenafil, tadalafil, vardenafil acts by inhibiting cGMP-specific phosphodiesterase type 5 (phosphodiesterase 5, PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.

ER+ bc

Tamoxifen - serm

Ethylene glycol // methanol intoxication

fomepizole (alcohol dehydrogenase inhibitor)

Haemophilus influenze (b)

Rifampin (prophylaxis) - inhibits DNA dependent RNA synthesis (bacterial)

GAD

SSRI, SNRI, (buspirone second line)

Heparin reversal

protamine sulfate

HER2/neu (+) bc

Trastuzumab

Hyperaldosteronism

sprionolactone

hypercholesterolemia

statin

hypertrglyceridemia

fibrate

immedate anticoagulation

heparin

inferitlity

leuprolide(GnRH agonist), GnRH (pulsatile), clomiphene (causes release of gonadotrophin by hypothalamus)

influenza

oseltamivir, zanamivir

kawasaki

IVIG, high-dose aspirin

Legionella pneuophila

macrolides (e.g. azithromycin)

long term anticoagulation

warfarin, dabigatran, rvaroxaban, apixaban

malaria

chloroquine, mefloquine, atovaquone/proguanil (for blood schizont), primaquine (for liver hypnozioite)

malignant hyperthermia

dantrolene

medical abortion

mifeprisone

migraine

abortive (sumatiptan, NSAID), Prophylaxis (propanolol, topiramate (anticonvulsant), CCBs, amitryptaline)

Disease modifiers (Beta-interferon, natlizumab=>a4-integrin) for acute flares (use IV steroids)

Mycobacterium tuberculosis

rifampin isoniazid pyrazinamide ethambutol

Neisseria gonorrhoeae

ceftriaxone (add doxycycline to cover likely concurrent Chlamydia trachomatis)

Nueural tube defect prevention

prenatal folic acid

osteomalacia/rickets

Vitamin D supplementation

Osteoporosis

Calcium/VitD supplemnation (prophylaxis); bisphosphonate, PTH analogs, SERMs, calcitonin, denosumab (binds to and inhibits RANKL) (treatment)

Patent DA

Close with indomethacin; open or maintian with PGE analogs

pheochromocytoma

alpha anatagonists (phenoxybenzamine)

pneumocystis jirovecii

tmp-smx (prophylaxis in AIDS)

Prolactinoma

cabergoline/bromocriptine (dopamine agonists)

prostate adenocarcinoma / uterine fibroids

leuprolide, GnRH (continuous) - will result in decrease in LH/FSH

Prostate adenocarcinoma

flutamide - selective AR antagonist

pseudomonas aeruginosa

antipseudomonal penicllins, aminoglycosides, carbapenems

pulmonary arterial hypertension (idio)

sildenafil, bosentan, epoprostenol

rickettsia rickettsii

doxycycline, chloramphenicol

schizophrenia - negative

atypical antipsychotics

schizophrenia - positive

typical and atypical antipsychotics

SIADH

Fluid restriction, iv hypertonic saline, conivaptan/tolvaptan, demeclocyline

sickle cell

hydroxyurea (increase fetal hemoglobin)

sporothrix schenckii

itraconazole, oral potassium iodide

stable angina

sublingual nitroglycerin

s aureus

MSSA: nafcillin, oxacillin, dicloxacillin MRSA: vancomycin, daptomycin, linezolid, ceftaroline

strep bovis (gallolyticus)

penicillin prophylaxis, evaution ofr colon cancer in linked to endocarditis

s penumoniae

penicillin/cephalosporin (systemic infection, penumonia), vancomycin (meningitis)

temporal arteritis

high does steroids

tonic clonic seizure

levetiracetam, phenytoin, valproate, carbamazepine

toxoplasma gondii

sulfadizaine + pyrimethamine

treponema pallidum

penicillin

trichomonas vaginalis

metronidazole (patient and partner)

trigeminal neuralgia (tic douloureux)

carbamazepine

ulcerative colitis

5-ASA preaprations (e.g. mesalamine), 6-mercaptopurine, infliximab, colectomy

UTI prophylaxis

TMP-SMX

Warfarin reversal

FFP (acute), VIT-K (chronic)