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Therapeutics Test 2 > CKD2 > Flashcards

CKD2 Flashcards

1
Q

what is the sodium restriction amount for controlling CKD progression

A

less than 2 g per day

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2
Q

what seemingly irrelevant thing should be evaluated in adults with newly identified CKD

A

lipid profile

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3
Q

who should use statin or statin/ezetimibe combinations as 1st line for dyslipidemia control w/ CKD

A

people over 50 w/ a GFR less than 60

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4
Q

why should NSAIDs be avoided in CKD

A

effect affarant arterioles

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5
Q

what meds should be avoided in CKD

A
  1. NSAIDs
  2. K supplements
  3. Enemas w/ phosphorous
  4. med’s with Magnesium or Al
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6
Q

whats the formula for BSH

what is preferred BSH/BMI in CKD

A 
square root((height (cm) x wt)/3600)
20-25
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7
Q

at what GFR do complications usually start

A

below 60

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8
Q

what are two important CKD complications

A

anemia

CKD-mineral and bone disorder

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9
Q

what causes anemia in CKD

A

primarily reduced erythropoietin production in kidneys

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10
Q

what is the hemoglobin levels to diagnosis anemia

A

less than 13.5 in males

less than 12 in females

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11
Q

what is responsible for storage of iron

A

serum ferritin

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12
Q

what is the protein that carries iron

A

TSAT

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13
Q

what are normal TIBC levels

A

250-450

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14
Q

what do elevated TIBC levels mean

A

iron deficiency

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15
Q

what are normal serum ferritin levels

A

200-380

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16
Q

what are normal serumiron levels

A

35-165

17
Q

what vitamin deficiencies can cause anemia

A

vitamin B12

folate levels

18
Q

what are goal hemoglobin levels in anemic pt’s with CKD

A

11-12

19
Q

ESA’s should not be used be used to maintain an Hgb level above what?

A

11.5

20
Q

what are the TSAT goal levels in anemic CKD pts

A

greater than 20

21
Q

what are the goal serum levels in anemic pts with CKD

A

greater than 100

22
Q

what should be monitored during iron replacement therapy

A

TSAT
serum ferritin
Hemoglobin

23
Q

what are the PO doses of iron therapy for stage 3-5 CKD

A

200 mg elemental iron/day

24
Q

what is the IV dose for iron therapy with hemodialysis

A

1 gram in divided doses

25
Q

how much iron is in a 324 mg tab of ferrous fumarate

A

106 mg elemental iron

26
Q

how much iron is in a 325 mg tab of ferrous sulfate

A

65 mg elemental iron

27
Q

how much iron is in a 324 mg tab of ferrous gluconate

A

38 mg elemental iron

28
Q

what is the onset time for PO iron supplements?

when will hemoglobin start to increase

A

3-10 days

2-4 weeks

29
Q

how long does reticulocytosis take to set in

A

5-10 days

Therapeutics Test 2 (31 decks)

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