Chronic Inflammation & Adaptive Immunity Flashcards
Professional antigen presenting cells
Macrophages
Dendritic cells
B cells
Main cast of adaptive immunity
T and B cells
Plasma cells
Dendritic cells
Macrophages
Who turns into plasma cells
B cells
Naive CD4 cells turn into…
T-helper cells
Naive CD8 cells turn into…
Cytotoxic t cells
What do T helper cells do (genral)
Help macrophages kill engulfed pathogens
Help B cells produce antibodies
What do cytotoxic t-cells do (general)
Directly kill cells infected with toxin
What happens during recruitment
Activated T and B cells stimulated to divide –> clonal expansion
What do T cells need for recognition
for the antigen to be bound to MHC
What does MHC stand for
Major histocompatibility complex
What cells is MHC - I present on
All of them
Which T cell does MHC - I bind to
CD8 (cytotoxic)
MHC - I presents antigen from……….the cell
inside
Which T cells does MHC - II bind to
CD4 (helper)
MHC - II presents antigen taken from………..the cell
outside
