Chpt 26-Interstitial Lung Disease Flashcards

1
Q

What impairs gas exchange in interstitial lung disease

A

Vq mismatching
Shunt
Decreased diffusion across interstitium

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2
Q

Signs and symptoms of ild

A

Dyspnea

Nonproductive cough

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3
Q

What are breath sounds with ild

A

Bilateral fine inspiratory crackles

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4
Q

What does chest X-ray with ild look like

A

Reduced lung volume with bilateral opacities

Ipf will have honeycomb appearance

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5
Q

What will present on pft for ild

A

Restrictive pattern
Reduced lung volumes
Reduced dlco

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6
Q

Normal spirometry but reduced dlco suggests?

A

Ipf and emphysema

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7
Q

Patients who develop ground glass opacities within 6. Months of radiation can be treated with

A

Oral corticosteroids for acute inflammation

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8
Q

Treatment for patients who develop ild more than 6 months post radiation can be treated with

A

Supportive care only, corticosteroids don’t help

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9
Q

Bleomycin induced ild is made worse by

A

High levels of oxygen

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10
Q

What is hypersensitivity pneumonitis

A

A cell mediated immune reaction to inhaled agents

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11
Q

Hypersensitivity pneumonitis will cause a reaction after?

A

Previously being exposed to an irritant, the patient will react on reexposure

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12
Q

Symptoms of hypersensitivity pneumonitis

A
Dyspnea 
Chest pain
Fever
Chills
Malaise 
Productive cough
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13
Q

Common antigens that cause hypersensitivity pneumonitis include

A

Bacteria-mushroom compost, mouldy hay, heated water reservoirs
Fungi-mouldy hay, barley, cheese, water, damp wood
Chemicals-paint, plastic, resin

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14
Q

Treatment for hypersensitivity pneumonitis

A

Avoiding triggers

Corticosteroids

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15
Q

What are the three most common occupational diseases

A

Asbestosis
Chronic silicosis
Coal workers pneumoconiosis

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16
Q

What would you expect on a chest X-ray of a patient with asbestosis

A
Plaques
Fibrosis
Effusions
Atelectasis 
Parenchyma scarring
17
Q

What increases risk of lung cancer synergistically

A

Asbestos exposure and cigarette smoking

18
Q

Symptoms of benign asbestos pleural effusions

A

Chest pain, fever and dyspnea

19
Q

Treatment for benign asbestos pleural effusions

A

Draining the effusion to reduce symptoms

20
Q

Treatment for asbestosis

A

Provide supportive care as patients are typically too old for lung transplant

21
Q

Jobs that have high risk of asbestos exposure

A

Ship building and insulation work

22
Q

Occupations that have exposure to silica

A

Mining
Tunneling
Sandblasting
Foundry work

23
Q

Chest X-ray in silicosis will present as

A

Upper lung abnormalities with small nodular opacities in central lung

24
Q

What would pft findings be in chronic silicosis

A

Mixed obstructive and restrictive with reduced dlco

25
Q

Silicosis increases risk of

A

Lung cancer and active tb

26
Q

How does coal workers pneumoconiosis develop

A

Chronic inhalation of coal dust

27
Q

How are exacerbation of silicosis and pneumococcus treated

A

Antibiotics and corticosteroids

28
Q

What connective tissue disorders have ild as a known complication

A

Scleroderma
Rheumatoid arthritis
Sjögren’s syndrome
Systemic lupus

29
Q

Symptoms of connective tissue disease with pulmonary involvement

A

Dyspnea

Cough

30
Q

Breath sounds with connective tissue it’s ease and ild

A

Wheezing, crackles or pleural rub

31
Q

What is the most common ild

A

Sarcoidosis

32
Q

Granulomas form in ?

A

Sarcoidosis

33
Q

What increases risk of ipf

A

Exposure to metal or farming dust

Smoking

34
Q

Ipf patients typically die within

A

4 years of diagnosis