Chpt 26-Interstitial Lung Disease Flashcards

1
Q

What impairs gas exchange in interstitial lung disease

A

Vq mismatching
Shunt
Decreased diffusion across interstitium

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2
Q

Signs and symptoms of ild

A

Dyspnea

Nonproductive cough

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3
Q

What are breath sounds with ild

A

Bilateral fine inspiratory crackles

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4
Q

What does chest X-ray with ild look like

A

Reduced lung volume with bilateral opacities

Ipf will have honeycomb appearance

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5
Q

What will present on pft for ild

A

Restrictive pattern
Reduced lung volumes
Reduced dlco

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6
Q

Normal spirometry but reduced dlco suggests?

A

Ipf and emphysema

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7
Q

Patients who develop ground glass opacities within 6. Months of radiation can be treated with

A

Oral corticosteroids for acute inflammation

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8
Q

Treatment for patients who develop ild more than 6 months post radiation can be treated with

A

Supportive care only, corticosteroids don’t help

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9
Q

Bleomycin induced ild is made worse by

A

High levels of oxygen

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10
Q

What is hypersensitivity pneumonitis

A

A cell mediated immune reaction to inhaled agents

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11
Q

Hypersensitivity pneumonitis will cause a reaction after?

A

Previously being exposed to an irritant, the patient will react on reexposure

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12
Q

Symptoms of hypersensitivity pneumonitis

A
Dyspnea 
Chest pain
Fever
Chills
Malaise 
Productive cough
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13
Q

Common antigens that cause hypersensitivity pneumonitis include

A

Bacteria-mushroom compost, mouldy hay, heated water reservoirs
Fungi-mouldy hay, barley, cheese, water, damp wood
Chemicals-paint, plastic, resin

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14
Q

Treatment for hypersensitivity pneumonitis

A

Avoiding triggers

Corticosteroids

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15
Q

What are the three most common occupational diseases

A

Asbestosis
Chronic silicosis
Coal workers pneumoconiosis

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16
Q

What would you expect on a chest X-ray of a patient with asbestosis

A
Plaques
Fibrosis
Effusions
Atelectasis 
Parenchyma scarring
17
Q

What increases risk of lung cancer synergistically

A

Asbestos exposure and cigarette smoking

18
Q

Symptoms of benign asbestos pleural effusions

A

Chest pain, fever and dyspnea

19
Q

Treatment for benign asbestos pleural effusions

A

Draining the effusion to reduce symptoms

20
Q

Treatment for asbestosis

A

Provide supportive care as patients are typically too old for lung transplant

21
Q

Jobs that have high risk of asbestos exposure

A

Ship building and insulation work

22
Q

Occupations that have exposure to silica

A

Mining
Tunneling
Sandblasting
Foundry work

23
Q

Chest X-ray in silicosis will present as

A

Upper lung abnormalities with small nodular opacities in central lung

24
Q

What would pft findings be in chronic silicosis

A

Mixed obstructive and restrictive with reduced dlco

25
Silicosis increases risk of
Lung cancer and active tb
26
How does coal workers pneumoconiosis develop
Chronic inhalation of coal dust
27
How are exacerbation of silicosis and pneumococcus treated
Antibiotics and corticosteroids
28
What connective tissue disorders have ild as a known complication
Scleroderma Rheumatoid arthritis Sjögren’s syndrome Systemic lupus
29
Symptoms of connective tissue disease with pulmonary involvement
Dyspnea | Cough
30
Breath sounds with connective tissue it’s ease and ild
Wheezing, crackles or pleural rub
31
What is the most common ild
Sarcoidosis
32
Granulomas form in ?
Sarcoidosis
33
What increases risk of ipf
Exposure to metal or farming dust | Smoking
34
Ipf patients typically die within
4 years of diagnosis