Chapter 29-ARDS Flashcards

1
Q

What causes pulmonary edema

A

When the rate of leakage into the lungs exceeds the lungs capacity to remove fluid

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2
Q

How do the lungs clear fluid

A

Lymphatic drainage

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3
Q

Net exchange of fluid between intravascular space and lung interstitum is controlled by

A

Hydrostatic and osmotic pressure within the blood and interstitum

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4
Q

Capillary hydrostatic and interstitial osmotic forces are normally (more/less) than the capillary osmotic and interstitial hydrostatic forces opposing

A

More

This encourages a small fraction of cardiac output from the capillaries into the interstitial space

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5
Q

What is seen on a chest X-ray with pulmonary edema

A

Kerley b lines

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6
Q

Large increases in interstitial hydrostatic pressure are caused by

A

Small increases in lung fluid content

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7
Q

Hydrostatic pulmonary edema occurs when?

A

The pressure or volume of water exceeds the lungs ability to remove fluid and the alveoli flood

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8
Q

Non hydrostatic pulmonary edema occurs when?

A

There is a hole in the interstitum which fluid leaks through

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9
Q

What are common cardiac causes of hydrostatic pulmonary edema

A

Left ventricular failure

Valve disease

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10
Q

What are volume related causes of hydrostatic pulmonary edema

A

Excessive fluids
Renal or liver failure
Hypoalbuminemia

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11
Q

Hydrostatic pulmonary edema causes what type of pleural fluid

A

Transudate fluid

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12
Q

Non hydrostatic pulmonary edema causes what type of pleural fluid

A

Exudate

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13
Q

Ards is caused by

A

Non hydrostatic pulmonary edema

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14
Q

Congestive heart failure is caused by

A

Hydrostatic pulmonary edema

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15
Q

Symptoms that present in both ards and chf

A

Anxiety
Dyspnea
Tachypnea
Hypoxemia

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16
Q

Features favouring chf

A

Diffuse, bilateral infiltrates
Elevated pcwp
Response to diuretics
Transudate fluid

17
Q

Features favouring ards

A

Asymmetric infiltrates on cxr
Little to no improvement with diuretics in first 24 hrs
Exudate fluid

18
Q

Risk factors of ards

A
Pneumonia
Aspiration
Near drowning
Sepsis
Trauma
Burns 
Pancreatis
19
Q

Chf typically presents with

A

Caridomegaly
Perihilar infiltrates
Pleural effusions

20
Q

Ards typically presents with

A

Air bronchgrams
Alveolar infiltrates
Normal cardiac size

21
Q

When is the educative phase

22
Q

When is the fibroproliferative phase

A

3 days- weeks

23
Q

What happens in the exudaitive phase

A

Damage to alveoli and blood vessels
Influx of fluid and cells into interstitial space and alveoli
Fully reversible if the cause is found and treated early

24
Q

What causes barotrauma

A

High pressures rupturing alveoli

25
What is the result of barotrauma
Air leaks outside of alveoli causing pneumothorax or pneumomediastinum
26
What is volutrauma
Stretch injury caused by high tidal volumes
27
What happens to alveoli in volutrauma
Overstretching results in leaky alveolar capillary walls which triggers an inflammatory cascade
28
What is the risk with high respiratory rates? ( 35+)
Can cause auto peep and impaired perfusion
29
Where is consolidation the worst in ards
Dependant lung regions (posterior regions when patient is supine)
30
How does proning work?
We are putting the good parts of the lungs down to improve V/q mismatch
31
How do vasodilator work in ards
Well ventilated areas of the lungs receive mist of the vasodilator. This means well ventilated areas receive a greater portion of blood flow, reducing v/q mismatch
32
Two examples of pul Kmart vasodilators
Epoprostenol | Nitric oxide
33
When should inhaled vasodilators be considered in ards
Pf less than 80
34
When should proning be done in ards
Pf less than 150
35
Treatments for ards?
Ventilation with low tidal volumes Proning Inhaled vasodilators Ecmo