Chapter35-Airway pharmacology Flashcards

1
Q

What are advantages to using inhaled drugs over systemic ?

A

Smaller doses
Less side effects
Rapid drug onset

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2
Q

What is pharmacokinetics

A

How the body absorbs and distributes the drug

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3
Q

What is pharmacodynamics

A

How the drug causes its effects in the body

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4
Q

Adrenergic is the same as

A

Sympathetic

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5
Q

Cholinergic is the same as

A

Parasympathetic

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6
Q

Drugs that activate receptors to cause an action are called

A

Agonists

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7
Q

Drugs that block receptors to cause an action are called

A

Antagonists

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8
Q

Adrenergic agonists would activate which receptors that respond to?

A

Epi

Norepinephrine

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9
Q

Adrenergic antagonists block receptors that respond to

A

Epi

Norepinephrine

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10
Q

Cholinergic agonists stimulate receptors that respond to

A

Ach

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11
Q

Anti cholinergic block receptors for?

A

Ach

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12
Q

A drug that stimulates ach receptors at parasympathetic nerve ending sites is called ?

A

Muscarinic

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13
Q

Beta 1 receptors cause what effects

A

Increased heart rate and force

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14
Q

Beta 2 activation causes

A

Bronchodilation, vasodilation, and increased submucosal gland secretion

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15
Q

Alpha 1 activation causes?

A

Vasoconstriction , increased fluid secretion of submucosal glands

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16
Q

M3 activation causes what effects?

A

Bronchocinstriction

Vasodilation.

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17
Q

Saba drugs include

A

Salbutamol

Terbutaline

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18
Q

Airomir or ventolin generic name

A

Salbutamol

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19
Q

Bricanyl generic name

A

Terbutaline

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20
Q

Sama drugs include

A

Ipratropium

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21
Q

Atrovent generic name

A

Ipratropium

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22
Q

Ultra long acting anti muscarinic drugs include

A

Aclidinium
Tiotropium
Glycopyrronium
Umeclidinium

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23
Q

Tudorza generic name

A

Aclidinium

24
Q

Laba drugs include

A

Formoterol
Indacaterol
Salmeterol

25
Q

Oxeze generic name

A

Formoterol

26
Q

Onbrez generic name

A

Indacaterol

27
Q

Serevent generic name

A

Salmeterol

28
Q

Spiriva generic name

A

Tiotropium

29
Q

Incruse generic name

A

Umeclidinium

30
Q

Seebri generic name

A

Glycopyrronium

31
Q

When is racemic epi indicates

A

Croup
Epiglottitis
Post extubation stridor
Control airway bleeding during endoscopy

32
Q

How does racemic epi work

A

Has a strong vasoconstriction effect to reduce airway swelling

33
Q

Beta 2 agonists are adrenergic agonists or cholinergic agonists?

A

Adrenergic

34
Q

What drug class is racemic epi

A

Catecholamine

35
Q

Alpha receptor stimulation causes?

A

Vasoconstriction and increases bp

36
Q

Beta-1-stimulation causes?

A

Increased heart rate and myocardial contractility

37
Q

Beta 2 stimulation causes?

A

Bronchodilation, increased mucocilary activity and inhibits inflammatory mediator release

38
Q

Lamas are also known as

A

Anticholinergics

39
Q

Side effects of lama

A

Wash hands as can cause glaucoma

Dry mouth or throat

40
Q

Side effects of ics

A

Oral thrush

41
Q

Ics drugs include

A
Ciclesonide
Fluticasone
Mometasone
Beclomethasone
Budesonide
42
Q

Alvesco generic name

A

Ciclesonice

43
Q

Arunity drug name

A

Fluticasone furoate

44
Q

Asmanex generic name

A

Mometasone

45
Q

Flovent generic name

A

Fluticasone propionate

46
Q

Pulmicort drug name

A

Budesonide

47
Q

Qvar drug name

A

Beclomethasone

48
Q

Ics/laba drugs

A

Advair
Brio
Symbicort
Zenhale

49
Q

Advair contains

A

Fluticasone and salmeterol

50
Q

Breo contains

A

Flitucasone and vilanterol

51
Q

Symbicort contains

A

Formoterol and budesonide

52
Q

Zenhale contains

A

Formoterol and mometasone

53
Q

Laba/lama drugs include

A

Anoro
Dukalir
Inspiloto
Ultibro

54
Q

Anoro Ellipta contains

A

Umeclidinium and vilanterol

55
Q

Dukalir contains

A

Formoterol and aclidnium

56
Q

Inspiloto contains

A

Tiotropium and olodaterol

57
Q

Ultibro contains

A

Indacaterol and glycopyrronium